Aversive memory formation in humans involves an amygdala-hippocampus phase code
The amygdala facilitates memory encoding in the hippocampus. Here the authors show, using simultaneous intracranial recordings from these regions, that emotional memory encoding is mediated by the amygdala theta phase to which hippocampal gamma activity and neuronal firing is coupled.
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-33828-2 |
| _version_ | 1811335282333581312 |
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| author | Manuela Costa Diego Lozano-Soldevilla Antonio Gil-Nagel Rafael Toledano Carina R. Oehrn Lukas Kunz Mar Yebra Costantino Mendez-Bertolo Lennart Stieglitz Johannes Sarnthein Nikolai Axmacher Stephan Moratti Bryan A. Strange |
| author_facet | Manuela Costa Diego Lozano-Soldevilla Antonio Gil-Nagel Rafael Toledano Carina R. Oehrn Lukas Kunz Mar Yebra Costantino Mendez-Bertolo Lennart Stieglitz Johannes Sarnthein Nikolai Axmacher Stephan Moratti Bryan A. Strange |
| author_sort | Manuela Costa |
| collection | DOAJ |
| description | The amygdala facilitates memory encoding in the hippocampus. Here the authors show, using simultaneous intracranial recordings from these regions, that emotional memory encoding is mediated by the amygdala theta phase to which hippocampal gamma activity and neuronal firing is coupled. |
| first_indexed | 2024-04-13T17:21:52Z |
| format | Article |
| id | doaj.art-f267ccc3631b4c4d9436df55d7586b16 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T17:21:52Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-f267ccc3631b4c4d9436df55d7586b162022-12-22T02:37:58ZengNature PortfolioNature Communications2041-17232022-10-0113111610.1038/s41467-022-33828-2Aversive memory formation in humans involves an amygdala-hippocampus phase codeManuela Costa0Diego Lozano-Soldevilla1Antonio Gil-Nagel2Rafael Toledano3Carina R. Oehrn4Lukas Kunz5Mar Yebra6Costantino Mendez-Bertolo7Lennart Stieglitz8Johannes Sarnthein9Nikolai Axmacher10Stephan Moratti11Bryan A. Strange12Laboratory for Clinical Neuroscience, Center for Biomedical Technology, Universidad Politécnica de Madrid, IdISSCLaboratory for Clinical Neuroscience, Center for Biomedical Technology, Universidad Politécnica de Madrid, IdISSCEpilepsy Unit, Department of Neurology, Hospital Ruber InternacionalEpilepsy Unit, Department of Neurology, Hospital Ruber InternacionalDepartment of Neurological Surgery, University of CaliforniaDepartment of Biomedical Engineering, Columbia UniversityLaboratory for Clinical Neuroscience, Center for Biomedical Technology, Universidad Politécnica de Madrid, IdISSCLaboratory for Clinical Neuroscience, Center for Biomedical Technology, Universidad Politécnica de Madrid, IdISSCDepartment of Neurosurgery, University Hospital Zurich, University of ZurichDepartment of Neurosurgery, University Hospital Zurich, University of ZurichDepartment of Neuropsychology, Institute of Cognitive Neuroscience, Faculty of Psychology, Ruhr University BochumLaboratory for Clinical Neuroscience, Center for Biomedical Technology, Universidad Politécnica de Madrid, IdISSCLaboratory for Clinical Neuroscience, Center for Biomedical Technology, Universidad Politécnica de Madrid, IdISSCThe amygdala facilitates memory encoding in the hippocampus. Here the authors show, using simultaneous intracranial recordings from these regions, that emotional memory encoding is mediated by the amygdala theta phase to which hippocampal gamma activity and neuronal firing is coupled.https://doi.org/10.1038/s41467-022-33828-2 |
| spellingShingle | Manuela Costa Diego Lozano-Soldevilla Antonio Gil-Nagel Rafael Toledano Carina R. Oehrn Lukas Kunz Mar Yebra Costantino Mendez-Bertolo Lennart Stieglitz Johannes Sarnthein Nikolai Axmacher Stephan Moratti Bryan A. Strange Aversive memory formation in humans involves an amygdala-hippocampus phase code Nature Communications |
| title | Aversive memory formation in humans involves an amygdala-hippocampus phase code |
| title_full | Aversive memory formation in humans involves an amygdala-hippocampus phase code |
| title_fullStr | Aversive memory formation in humans involves an amygdala-hippocampus phase code |
| title_full_unstemmed | Aversive memory formation in humans involves an amygdala-hippocampus phase code |
| title_short | Aversive memory formation in humans involves an amygdala-hippocampus phase code |
| title_sort | aversive memory formation in humans involves an amygdala hippocampus phase code |
| url | https://doi.org/10.1038/s41467-022-33828-2 |
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