Structure-function studies reveal ComEA contains an oligomerization domain essential for transformation in gram-positive bacteria

Structure-function studies reveal ComEA contains an oligomerization domain essential for transformation in gram-positive bacteria

ComEA is a DNA-binding protein required for DNA uptake during bacterial transformation. Here, Ahmed et al. determine X-ray crystal structures of ComEA from Gram-positive bacteria, identifying a domain that is absent in Gram-negative bacteria and drives ComEA oligomerization, which is required for tr...

Full description

Bibliographic Details
Main Authors: Ishtiyaq Ahmed, Jeanette Hahn, Amy Henrickson, Faisal Tarique Khaja, Borries Demeler, David Dubnau, Matthew B. Neiditch
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35129-0

Similar Items

Similar Items