PAM-Expanded Streptococcus thermophilus Cas9 C-to-T and C-to-G Base Editors for Programmable Base Editing in Mycobacteria
New therapeutic strategies for the rapid and effective treatment of drug-resistant tuberculosis are highly desirable, and their development can be drastically accelerated by facile genetic manipulation methods in Mycobacterium tuberculosis (M. tuberculosis). Clustered regularly interspaced short pal...
Main Authors: | Hongyuan Zhang, Yifei Zhang, Wei-Xiao Wang, Weizhong Chen, Xia Zhang, Xingxu Huang, Wei Chen, Quanjiang Ji |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-08-01
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Series: | Engineering |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S209580992200282X |
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