Adipose tissue secretory profile and cardiometabolic risk in obesity
Adipose tissue is not only an energy storage but also the largest endocrine organ in the body. The protein factors secreted from adipose tissue are collectively referred to as adipokines. Depending on the anatomical locations, adipose tissue depots show different metabolic and endocrine properties....
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-11-01
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| Series: | Endocrine and Metabolic Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666396120300157 |
| _version_ | 1818721707265884160 |
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| author | Pengcheng Zhang Daniels Konja Yu Wang |
| author_facet | Pengcheng Zhang Daniels Konja Yu Wang |
| author_sort | Pengcheng Zhang |
| collection | DOAJ |
| description | Adipose tissue is not only an energy storage but also the largest endocrine organ in the body. The protein factors secreted from adipose tissue are collectively referred to as adipokines. Depending on the anatomical locations, adipose tissue depots show different metabolic and endocrine properties. Thus, the expansion and accumulation of adipose tissue exhibit regional variations that affect the cardiometabolic outcomes in distinctive manners. The present review includes subcutaneous, abdominal visceral, perivascular and epicardial adipose tissues for a brief discussion on their roles in the development of obesity-associated cardiometabolic diseases, with a special focus on the secretory profiles of adipokines. |
| first_indexed | 2024-12-17T20:43:00Z |
| format | Article |
| id | doaj.art-f27f1cf177c44da4a9abed643aa290c5 |
| institution | Directory Open Access Journal |
| issn | 2666-3961 |
| language | English |
| last_indexed | 2024-12-17T20:43:00Z |
| publishDate | 2020-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Endocrine and Metabolic Science |
| spelling | doaj.art-f27f1cf177c44da4a9abed643aa290c52022-12-21T21:33:15ZengElsevierEndocrine and Metabolic Science2666-39612020-11-0113100061Adipose tissue secretory profile and cardiometabolic risk in obesityPengcheng Zhang0Daniels Konja1Yu Wang2The State Key Laboratory of Pharmaceutical Biotechnology and the Department of Pharmacology and Pharmacy, the University of Hong Kong, Hong Kong SAR, ChinaThe State Key Laboratory of Pharmaceutical Biotechnology and the Department of Pharmacology and Pharmacy, the University of Hong Kong, Hong Kong SAR, ChinaCorresponding author; The State Key Laboratory of Pharmaceutical Biotechnology and the Department of Pharmacology and Pharmacy, the University of Hong Kong, Hong Kong SAR, ChinaAdipose tissue is not only an energy storage but also the largest endocrine organ in the body. The protein factors secreted from adipose tissue are collectively referred to as adipokines. Depending on the anatomical locations, adipose tissue depots show different metabolic and endocrine properties. Thus, the expansion and accumulation of adipose tissue exhibit regional variations that affect the cardiometabolic outcomes in distinctive manners. The present review includes subcutaneous, abdominal visceral, perivascular and epicardial adipose tissues for a brief discussion on their roles in the development of obesity-associated cardiometabolic diseases, with a special focus on the secretory profiles of adipokines.http://www.sciencedirect.com/science/article/pii/S2666396120300157AdipokinesAdiposityFat depotsCardiometbolic diseases |
| spellingShingle | Pengcheng Zhang Daniels Konja Yu Wang Adipose tissue secretory profile and cardiometabolic risk in obesity Endocrine and Metabolic Science Adipokines Adiposity Fat depots Cardiometbolic diseases |
| title | Adipose tissue secretory profile and cardiometabolic risk in obesity |
| title_full | Adipose tissue secretory profile and cardiometabolic risk in obesity |
| title_fullStr | Adipose tissue secretory profile and cardiometabolic risk in obesity |
| title_full_unstemmed | Adipose tissue secretory profile and cardiometabolic risk in obesity |
| title_short | Adipose tissue secretory profile and cardiometabolic risk in obesity |
| title_sort | adipose tissue secretory profile and cardiometabolic risk in obesity |
| topic | Adipokines Adiposity Fat depots Cardiometbolic diseases |
| url | http://www.sciencedirect.com/science/article/pii/S2666396120300157 |
| work_keys_str_mv | AT pengchengzhang adiposetissuesecretoryprofileandcardiometabolicriskinobesity AT danielskonja adiposetissuesecretoryprofileandcardiometabolicriskinobesity AT yuwang adiposetissuesecretoryprofileandcardiometabolicriskinobesity |