Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm Action
The urgency for the availability of new antibacterial/disinfectant agents has become a worldwide priority. At the same time, along with the extensive use of other metal nanoparticles (NPs), the investigation of magnetic NPs (MNPs) in antibacterial studies has turned out to be an increasingly attract...
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| 格式: | 文件 |
| 语言: | English |
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MDPI AG
2021-01-01
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| 丛编: | Antibiotics |
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| 在线阅读: | https://www.mdpi.com/2079-6382/10/2/119 |
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| author | Verdiana Marchianò Maria Salvador Amanda Moyano Gemma Gutiérrez María Matos Susana Yáñez-Vilar Yolanda Piñeiro José Rivas José C. Martínez-García Davide Peddis Maria C. Blanco-López Montserrat Rivas Nicoletta Ditaranto Nicola Cioffi |
| author_facet | Verdiana Marchianò Maria Salvador Amanda Moyano Gemma Gutiérrez María Matos Susana Yáñez-Vilar Yolanda Piñeiro José Rivas José C. Martínez-García Davide Peddis Maria C. Blanco-López Montserrat Rivas Nicoletta Ditaranto Nicola Cioffi |
| author_sort | Verdiana Marchianò |
| collection | DOAJ |
| description | The urgency for the availability of new antibacterial/disinfectant agents has become a worldwide priority. At the same time, along with the extensive use of other metal nanoparticles (NPs), the investigation of magnetic NPs (MNPs) in antibacterial studies has turned out to be an increasingly attractive research field. In this context, we present the preparation and characterization of superparamagnetic iron oxide NPs, electrodecorated with antimicrobial copper NPs, able to modulate the release of bioactive species not only by the NP’s stabilizer, but also through the application of a suitable magnetic field. Antimicrobial synergistic CuNPs stabilized by benzalkonium chloride have been used in the current study. We demonstrate the successful preparation of Cu@Fe<sub>3</sub>O<sub>4</sub> MNPs composites through morphological and spectroscopic results. Additionally, an extensive magnetic characterization is reported, along with hyperthermia-induced copper ionic release. On the basis of our results, we propose a new generation of antimicrobial magnetic nanomaterials, whose bioactivity can be also tuned by the application of a magnetic field. |
| first_indexed | 2024-03-09T03:36:02Z |
| format | Article |
| id | doaj.art-f282c8725b2044c0bfb1d80d6f772e97 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-09T03:36:02Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-f282c8725b2044c0bfb1d80d6f772e972023-12-03T14:49:24ZengMDPI AGAntibiotics2079-63822021-01-0110211910.3390/antibiotics10020119Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm ActionVerdiana Marchianò0Maria Salvador1Amanda Moyano2Gemma Gutiérrez3María Matos4Susana Yáñez-Vilar5Yolanda Piñeiro6José Rivas7José C. Martínez-García8Davide Peddis9Maria C. Blanco-López10Montserrat Rivas11Nicoletta Ditaranto12Nicola Cioffi13Department of Physical and Analytical Chemistry, University of Oviedo, 33006 Oviedo, SpainDepartment of Physics and IUTA, University of Oviedo, 33204 Gijon, SpainDepartment of Physical and Analytical Chemistry, University of Oviedo, 33006 Oviedo, SpainDepartment of Chemical Engineering, University of Oviedo, 33006 Oviedo, SpainDepartment of Chemical Engineering, University of Oviedo, 33006 Oviedo, SpainDepartment of Applied Physics, University of Santiago de Compostela, 15782 Santiago de Compostela, SpainDepartment of Applied Physics, University of Santiago de Compostela, 15782 Santiago de Compostela, SpainDepartment of Applied Physics, University of Santiago de Compostela, 15782 Santiago de Compostela, SpainDepartment of Physics and IUTA, University of Oviedo, 33204 Gijon, SpainIstituto di Struttura della Materia—Consiglio Nazionale delle Ricerche (CNR), Monterotondo Scalo (RM), 00016 Rome, ItalyDepartment of Physical and Analytical Chemistry, University of Oviedo, 33006 Oviedo, SpainDepartment of Physics and IUTA, University of Oviedo, 33204 Gijon, SpainDipartimento di Chimica and CSGI—Bari Unit, Università degli Studi di Bari Aldo Moro, 70125 Bari, ItalyDipartimento di Chimica and CSGI—Bari Unit, Università degli Studi di Bari Aldo Moro, 70125 Bari, ItalyThe urgency for the availability of new antibacterial/disinfectant agents has become a worldwide priority. At the same time, along with the extensive use of other metal nanoparticles (NPs), the investigation of magnetic NPs (MNPs) in antibacterial studies has turned out to be an increasingly attractive research field. In this context, we present the preparation and characterization of superparamagnetic iron oxide NPs, electrodecorated with antimicrobial copper NPs, able to modulate the release of bioactive species not only by the NP’s stabilizer, but also through the application of a suitable magnetic field. Antimicrobial synergistic CuNPs stabilized by benzalkonium chloride have been used in the current study. We demonstrate the successful preparation of Cu@Fe<sub>3</sub>O<sub>4</sub> MNPs composites through morphological and spectroscopic results. Additionally, an extensive magnetic characterization is reported, along with hyperthermia-induced copper ionic release. On the basis of our results, we propose a new generation of antimicrobial magnetic nanomaterials, whose bioactivity can be also tuned by the application of a magnetic field.https://www.mdpi.com/2079-6382/10/2/119copper nanoparticleSPIONsynergistic bioactivityhyperthermiaion release |
| spellingShingle | Verdiana Marchianò Maria Salvador Amanda Moyano Gemma Gutiérrez María Matos Susana Yáñez-Vilar Yolanda Piñeiro José Rivas José C. Martínez-García Davide Peddis Maria C. Blanco-López Montserrat Rivas Nicoletta Ditaranto Nicola Cioffi Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm Action Antibiotics copper nanoparticle SPION synergistic bioactivity hyperthermia ion release |
| title | Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm Action |
| title_full | Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm Action |
| title_fullStr | Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm Action |
| title_full_unstemmed | Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm Action |
| title_short | Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm Action |
| title_sort | electrodecoration and characterization of superparamagnetic iron oxide nanoparticles with bioactive synergistic nanocopper magnetic hyperthermia induced ionic release for anti biofilm action |
| topic | copper nanoparticle SPION synergistic bioactivity hyperthermia ion release |
| url | https://www.mdpi.com/2079-6382/10/2/119 |
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