Stroke impairs the control of isometric forces and muscle activations in the ipsilesional arm
Abstract Stroke often impairs the control of the contralesional arm, thus most survivors rely on the ipsilesional arm to perform daily living activities that require an efficient control of movements and forces. Whereas the ipsilesional arm is often called ‘unaffected’ or ‘unimpaired’, several studi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-09-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-96329-0 |
| _version_ | 1818993719587635200 |
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| author | Laura Pellegrino Martina Coscia Psiche Giannoni Lucio Marinelli Maura Casadio |
| author_facet | Laura Pellegrino Martina Coscia Psiche Giannoni Lucio Marinelli Maura Casadio |
| author_sort | Laura Pellegrino |
| collection | DOAJ |
| description | Abstract Stroke often impairs the control of the contralesional arm, thus most survivors rely on the ipsilesional arm to perform daily living activities that require an efficient control of movements and forces. Whereas the ipsilesional arm is often called ‘unaffected’ or ‘unimpaired’, several studies suggested that during dynamic tasks its kinematics and joint torques are altered. Is stroke also affecting the ability of the ipsilesional arm to produce isometric force, as when pushing or pulling a handle? Here, we address this question by analyzing behavioral performance and muscles’ activity when subjects applied an isometric force of 10 N in eight coplanar directions. We found that stroke affected the ability to apply well-controlled isometric forces with the ipsilesional arm, although to a minor extent compared to the contralesional arm. The spinal maps, the analysis of single muscle activities and the organization of muscle synergies highlighted that this effect was mainly associated with abnormal activity of proximal muscles with respect to matched controls, especially when pushing or pulling in lateral directions. |
| first_indexed | 2024-12-20T20:46:32Z |
| format | Article |
| id | doaj.art-f28328abf0c846bb9f0c6ea5132c8c86 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-20T20:46:32Z |
| publishDate | 2021-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-f28328abf0c846bb9f0c6ea5132c8c862022-12-21T19:27:02ZengNature PortfolioScientific Reports2045-23222021-09-0111111810.1038/s41598-021-96329-0Stroke impairs the control of isometric forces and muscle activations in the ipsilesional armLaura Pellegrino0Martina Coscia1Psiche Giannoni2Lucio Marinelli3Maura Casadio4Dept. Informatics, Bioengineering, Robotics and Systems Engineering, University of GenoaBertarelli Foundation Chair in Translational Neuroengineering, Ecole Polytechnique Federale de LausanneDept. Informatics, Bioengineering, Robotics and Systems Engineering, University of GenoaDivision of Clinical Neurophysiology, Department of Neuroscience, IRCCS Ospedale Policlinico San MartinoDept. Informatics, Bioengineering, Robotics and Systems Engineering, University of GenoaAbstract Stroke often impairs the control of the contralesional arm, thus most survivors rely on the ipsilesional arm to perform daily living activities that require an efficient control of movements and forces. Whereas the ipsilesional arm is often called ‘unaffected’ or ‘unimpaired’, several studies suggested that during dynamic tasks its kinematics and joint torques are altered. Is stroke also affecting the ability of the ipsilesional arm to produce isometric force, as when pushing or pulling a handle? Here, we address this question by analyzing behavioral performance and muscles’ activity when subjects applied an isometric force of 10 N in eight coplanar directions. We found that stroke affected the ability to apply well-controlled isometric forces with the ipsilesional arm, although to a minor extent compared to the contralesional arm. The spinal maps, the analysis of single muscle activities and the organization of muscle synergies highlighted that this effect was mainly associated with abnormal activity of proximal muscles with respect to matched controls, especially when pushing or pulling in lateral directions.https://doi.org/10.1038/s41598-021-96329-0 |
| spellingShingle | Laura Pellegrino Martina Coscia Psiche Giannoni Lucio Marinelli Maura Casadio Stroke impairs the control of isometric forces and muscle activations in the ipsilesional arm Scientific Reports |
| title | Stroke impairs the control of isometric forces and muscle activations in the ipsilesional arm |
| title_full | Stroke impairs the control of isometric forces and muscle activations in the ipsilesional arm |
| title_fullStr | Stroke impairs the control of isometric forces and muscle activations in the ipsilesional arm |
| title_full_unstemmed | Stroke impairs the control of isometric forces and muscle activations in the ipsilesional arm |
| title_short | Stroke impairs the control of isometric forces and muscle activations in the ipsilesional arm |
| title_sort | stroke impairs the control of isometric forces and muscle activations in the ipsilesional arm |
| url | https://doi.org/10.1038/s41598-021-96329-0 |
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