Low-Cost Surface Enhanced Raman Scattering for Bio-Probes
Raman Spectroscopy is a well-known method for identifying molecules by their spectroscopic “fingerprint”. In Surface Enhanced Raman Scattering (SERS), the presence of nanometallic surfaces in contact with the molecules enormously enhances the spectroscopic signal. Raman enhancing surfaces are often...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Solids |
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| Online Access: | https://www.mdpi.com/2673-6497/3/2/13 |
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| author | Blessing Adewumi Martin Feldman Debsmita Biswas Dongmei Cao Li Jiang Naga Korivi |
| author_facet | Blessing Adewumi Martin Feldman Debsmita Biswas Dongmei Cao Li Jiang Naga Korivi |
| author_sort | Blessing Adewumi |
| collection | DOAJ |
| description | Raman Spectroscopy is a well-known method for identifying molecules by their spectroscopic “fingerprint”. In Surface Enhanced Raman Scattering (SERS), the presence of nanometallic surfaces in contact with the molecules enormously enhances the spectroscopic signal. Raman enhancing surfaces are often fabricated lithographically or chemically, but the throughput is low and the equipment is expensive. In this work a SERS layer was formed by the self-assembly of silver nanospheres from a hexane suspension onto an imprinted thermoplastic sheet (PET). In addition, the SERS layer was transferred and securely bonded to other surfaces. This is an important attribute for probes into solid specimen. Raman spectra were obtained with Rhodamine 6G (R6G) solution concentrations ranging from 1 mm to 1 nm. The methods described here produced robust and sensitive SERS surfaces with inexpensive equipment, readily available materials, and with no chemical or lithographic steps. These may be critical concerns to laboratories faced with diminishing funding resources. |
| first_indexed | 2024-03-09T22:30:26Z |
| format | Article |
| id | doaj.art-f2834f2852cf4481a3670dba707d138e |
| institution | Directory Open Access Journal |
| issn | 2673-6497 |
| language | English |
| last_indexed | 2024-03-09T22:30:26Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Solids |
| spelling | doaj.art-f2834f2852cf4481a3670dba707d138e2023-11-23T18:59:35ZengMDPI AGSolids2673-64972022-04-013218820210.3390/solids3020013Low-Cost Surface Enhanced Raman Scattering for Bio-ProbesBlessing Adewumi0Martin Feldman1Debsmita Biswas2Dongmei Cao3Li Jiang4Naga Korivi5Division of Electrical and Computer Engineering, Louisiana State University, Baton Rouge, LA 70803, USADivision of Electrical and Computer Engineering, Louisiana State University, Baton Rouge, LA 70803, USADivision of Electrical and Computer Engineering, Louisiana State University, Baton Rouge, LA 70803, USAShared Instrumentation Facility, Louisiana State University, Baton Rouge, LA 70803, USADepartment of Electrical and Computer Engineering, Tuskegee University, Tuskegee, AL 36088, USADepartment of Electrical and Computer Engineering, Tuskegee University, Tuskegee, AL 36088, USARaman Spectroscopy is a well-known method for identifying molecules by their spectroscopic “fingerprint”. In Surface Enhanced Raman Scattering (SERS), the presence of nanometallic surfaces in contact with the molecules enormously enhances the spectroscopic signal. Raman enhancing surfaces are often fabricated lithographically or chemically, but the throughput is low and the equipment is expensive. In this work a SERS layer was formed by the self-assembly of silver nanospheres from a hexane suspension onto an imprinted thermoplastic sheet (PET). In addition, the SERS layer was transferred and securely bonded to other surfaces. This is an important attribute for probes into solid specimen. Raman spectra were obtained with Rhodamine 6G (R6G) solution concentrations ranging from 1 mm to 1 nm. The methods described here produced robust and sensitive SERS surfaces with inexpensive equipment, readily available materials, and with no chemical or lithographic steps. These may be critical concerns to laboratories faced with diminishing funding resources.https://www.mdpi.com/2673-6497/3/2/13SERSbiochemical probesimprinting |
| spellingShingle | Blessing Adewumi Martin Feldman Debsmita Biswas Dongmei Cao Li Jiang Naga Korivi Low-Cost Surface Enhanced Raman Scattering for Bio-Probes Solids SERS biochemical probes imprinting |
| title | Low-Cost Surface Enhanced Raman Scattering for Bio-Probes |
| title_full | Low-Cost Surface Enhanced Raman Scattering for Bio-Probes |
| title_fullStr | Low-Cost Surface Enhanced Raman Scattering for Bio-Probes |
| title_full_unstemmed | Low-Cost Surface Enhanced Raman Scattering for Bio-Probes |
| title_short | Low-Cost Surface Enhanced Raman Scattering for Bio-Probes |
| title_sort | low cost surface enhanced raman scattering for bio probes |
| topic | SERS biochemical probes imprinting |
| url | https://www.mdpi.com/2673-6497/3/2/13 |
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