Radiotherapy Induced Middle Ear Morbidities in Head and Neck Cancer Patients
Introduction Although post radiotherapy (RT) otological complications are complex and common, there is lack of data on its severity and spectrum. We intend to assess the incidence and severity of such ototoxicities in head neck cancer (HNCA) patients. Materials and Methods One year prospective s...
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| Format: | Article |
| Language: | English |
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The Association of Otolaryngologists of India, West Bengal
2021-06-01
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| Series: | Bengal Journal of Otolaryngology and Head Neck Surgery |
| Subjects: | |
| Online Access: | https://bjohns.in/journal3/index.php/bjohns/article/view/432 |
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| author | Adity Chakraborty Abhinandan Bhattacharjee Arnab Purakaystha Aakanksha Rathor Ridip Mazumdar |
| author_facet | Adity Chakraborty Abhinandan Bhattacharjee Arnab Purakaystha Aakanksha Rathor Ridip Mazumdar |
| author_sort | Adity Chakraborty |
| collection | DOAJ |
| description | Introduction
Although post radiotherapy (RT) otological complications are complex and common, there is lack of data on its severity and spectrum. We intend to assess the incidence and severity of such ototoxicities in head neck cancer (HNCA) patients.
Materials and Methods
One year prospective study was conducted on thirty cases of HNCA receiving radiotherapy. Audiometry and tympanometry changes were noted and severity is assessed using Common Toxicity Criteria (CTC) -v2.0 of the National Cancer Institute (NCI). Fisher's Exact Test with two-sided p value was used for comparison of the tympanometric changes.
Results
The mean age was 55.4 years. The commonest site of HNCA was oral cavity (30%) with 46.6 % in stage II. 40% of cases were in grade II, followed by 27% cases in Grade III. The commonest complaint was pain (86.6%), hearing loss (80%) and 40% post-RT cases reporting Type B curve (relative risk 0.67).
Conclusion
Post-irradiation pain and OME are a major concern in HNCA patients having grade II (NCI-CTC). Early detection and prophylactic measures will improve the quality of life in such group of patients. This result validates the need for formulating otological diagnostic strategy & therapeutic measures in patients receiving RT to mitigate post-irradiation ototoxicities. |
| first_indexed | 2024-03-07T17:49:22Z |
| format | Article |
| id | doaj.art-f28428dc1eff4e0a8e2a8962ed5d19bb |
| institution | Directory Open Access Journal |
| issn | 2395-2407 |
| language | English |
| last_indexed | 2024-03-07T17:49:22Z |
| publishDate | 2021-06-01 |
| publisher | The Association of Otolaryngologists of India, West Bengal |
| record_format | Article |
| series | Bengal Journal of Otolaryngology and Head Neck Surgery |
| spelling | doaj.art-f28428dc1eff4e0a8e2a8962ed5d19bb2024-03-02T14:25:18ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-24072021-06-01291Radiotherapy Induced Middle Ear Morbidities in Head and Neck Cancer PatientsAdity Chakraborty0Abhinandan Bhattacharjee1 Arnab Purakaystha2Aakanksha Rathor3 Ridip Mazumdar4Guwahati Medical College, ASsam 781006Silchar Medical College, Assam, 788014Silchar Medical College, Assam, 788014 Stanford University School of Medicine, CA, USASilchar Medical College, Assam 788014Introduction Although post radiotherapy (RT) otological complications are complex and common, there is lack of data on its severity and spectrum. We intend to assess the incidence and severity of such ototoxicities in head neck cancer (HNCA) patients. Materials and Methods One year prospective study was conducted on thirty cases of HNCA receiving radiotherapy. Audiometry and tympanometry changes were noted and severity is assessed using Common Toxicity Criteria (CTC) -v2.0 of the National Cancer Institute (NCI). Fisher's Exact Test with two-sided p value was used for comparison of the tympanometric changes. Results The mean age was 55.4 years. The commonest site of HNCA was oral cavity (30%) with 46.6 % in stage II. 40% of cases were in grade II, followed by 27% cases in Grade III. The commonest complaint was pain (86.6%), hearing loss (80%) and 40% post-RT cases reporting Type B curve (relative risk 0.67). Conclusion Post-irradiation pain and OME are a major concern in HNCA patients having grade II (NCI-CTC). Early detection and prophylactic measures will improve the quality of life in such group of patients. This result validates the need for formulating otological diagnostic strategy & therapeutic measures in patients receiving RT to mitigate post-irradiation ototoxicities.https://bjohns.in/journal3/index.php/bjohns/article/view/432Head and Neck NeoplasmsRadiotherapyMorbidity, EarProspective Study |
| spellingShingle | Adity Chakraborty Abhinandan Bhattacharjee Arnab Purakaystha Aakanksha Rathor Ridip Mazumdar Radiotherapy Induced Middle Ear Morbidities in Head and Neck Cancer Patients Bengal Journal of Otolaryngology and Head Neck Surgery Head and Neck Neoplasms Radiotherapy Morbidity, Ear Prospective Study |
| title | Radiotherapy Induced Middle Ear Morbidities in Head and Neck Cancer Patients |
| title_full | Radiotherapy Induced Middle Ear Morbidities in Head and Neck Cancer Patients |
| title_fullStr | Radiotherapy Induced Middle Ear Morbidities in Head and Neck Cancer Patients |
| title_full_unstemmed | Radiotherapy Induced Middle Ear Morbidities in Head and Neck Cancer Patients |
| title_short | Radiotherapy Induced Middle Ear Morbidities in Head and Neck Cancer Patients |
| title_sort | radiotherapy induced middle ear morbidities in head and neck cancer patients |
| topic | Head and Neck Neoplasms Radiotherapy Morbidity, Ear Prospective Study |
| url | https://bjohns.in/journal3/index.php/bjohns/article/view/432 |
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