Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review
Nowadays, various drugs on the market are becoming more and more resistant to numerous diseases, thus declining their efficacy for treatment purposes in human beings. Antibiotic resistance is one among the top listed threat around the world which eventually urged the discovery of new potent drugs fo...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2017-11-01
|
| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1660-3397/15/11/354 |
| _version_ | 1798043247160852480 |
|---|---|
| author | Sayed Asmat Ali Shah Najeeb Akhter Bibi Nazia Auckloo Ishrat Khan Yanbin Lu Kuiwu Wang Bin Wu Yue-Wei Guo |
| author_facet | Sayed Asmat Ali Shah Najeeb Akhter Bibi Nazia Auckloo Ishrat Khan Yanbin Lu Kuiwu Wang Bin Wu Yue-Wei Guo |
| author_sort | Sayed Asmat Ali Shah |
| collection | DOAJ |
| description | Nowadays, various drugs on the market are becoming more and more resistant to numerous diseases, thus declining their efficacy for treatment purposes in human beings. Antibiotic resistance is one among the top listed threat around the world which eventually urged the discovery of new potent drugs followed by an increase in the number of deaths caused by cancer due to chemotherapy resistance as well. Accordingly, marine cyanobacteria, being the oldest prokaryotic microorganisms belonging to a monophyletic group, have proven themselves as being able to generate pharmaceutically important natural products. They have long been known to produce distinct and structurally complex secondary metabolites including peptides, polyketides, alkaloids, lipids, and terpenes with potent biological properties and applications. As such, this review will focus on recently published novel compounds isolated from marine cyanobacteria along with their potential bioactivities such as antibacterial, antifungal, anticancer, anti-tuberculosis, immunosuppressive and anti-inflammatory capacities. Moreover, various structural classes, as well as their technological uses will also be discussed. |
| first_indexed | 2024-04-11T22:46:42Z |
| format | Article |
| id | doaj.art-f28572bb76304e27a32b243b7c4a0d17 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T22:46:42Z |
| publishDate | 2017-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-f28572bb76304e27a32b243b7c4a0d172022-12-22T03:58:44ZengMDPI AGMarine Drugs1660-33972017-11-01151135410.3390/md15110354md15110354Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A ReviewSayed Asmat Ali Shah0Najeeb Akhter1Bibi Nazia Auckloo2Ishrat Khan3Yanbin Lu4Kuiwu Wang5Bin Wu6Yue-Wei Guo7Ocean College, Zhejiang University, Hangzhou 310058, ChinaOcean College, Zhejiang University, Hangzhou 310058, ChinaOcean College, Zhejiang University, Hangzhou 310058, ChinaOcean College, Zhejiang University, Hangzhou 310058, ChinaDepartment of Applied Chemistry, Zhejiang Gongshang University, Hangzhou 310012, ChinaDepartment of Applied Chemistry, Zhejiang Gongshang University, Hangzhou 310012, ChinaOcean College, Zhejiang University, Hangzhou 310058, ChinaState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, ChinaNowadays, various drugs on the market are becoming more and more resistant to numerous diseases, thus declining their efficacy for treatment purposes in human beings. Antibiotic resistance is one among the top listed threat around the world which eventually urged the discovery of new potent drugs followed by an increase in the number of deaths caused by cancer due to chemotherapy resistance as well. Accordingly, marine cyanobacteria, being the oldest prokaryotic microorganisms belonging to a monophyletic group, have proven themselves as being able to generate pharmaceutically important natural products. They have long been known to produce distinct and structurally complex secondary metabolites including peptides, polyketides, alkaloids, lipids, and terpenes with potent biological properties and applications. As such, this review will focus on recently published novel compounds isolated from marine cyanobacteria along with their potential bioactivities such as antibacterial, antifungal, anticancer, anti-tuberculosis, immunosuppressive and anti-inflammatory capacities. Moreover, various structural classes, as well as their technological uses will also be discussed.https://www.mdpi.com/1660-3397/15/11/354cyanobacteriasecondary metabolitesbiological properties and applications |
| spellingShingle | Sayed Asmat Ali Shah Najeeb Akhter Bibi Nazia Auckloo Ishrat Khan Yanbin Lu Kuiwu Wang Bin Wu Yue-Wei Guo Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review Marine Drugs cyanobacteria secondary metabolites biological properties and applications |
| title | Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review |
| title_full | Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review |
| title_fullStr | Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review |
| title_full_unstemmed | Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review |
| title_short | Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review |
| title_sort | structural diversity biological properties and applications of natural products from cyanobacteria a review |
| topic | cyanobacteria secondary metabolites biological properties and applications |
| url | https://www.mdpi.com/1660-3397/15/11/354 |
| work_keys_str_mv | AT sayedasmatalishah structuraldiversitybiologicalpropertiesandapplicationsofnaturalproductsfromcyanobacteriaareview AT najeebakhter structuraldiversitybiologicalpropertiesandapplicationsofnaturalproductsfromcyanobacteriaareview AT bibinaziaauckloo structuraldiversitybiologicalpropertiesandapplicationsofnaturalproductsfromcyanobacteriaareview AT ishratkhan structuraldiversitybiologicalpropertiesandapplicationsofnaturalproductsfromcyanobacteriaareview AT yanbinlu structuraldiversitybiologicalpropertiesandapplicationsofnaturalproductsfromcyanobacteriaareview AT kuiwuwang structuraldiversitybiologicalpropertiesandapplicationsofnaturalproductsfromcyanobacteriaareview AT binwu structuraldiversitybiologicalpropertiesandapplicationsofnaturalproductsfromcyanobacteriaareview AT yueweiguo structuraldiversitybiologicalpropertiesandapplicationsofnaturalproductsfromcyanobacteriaareview |