Long term outcome of surgical treatment of chondroblastoma: analysis of local control and growth plate/articular cartilage related complications
Abstract Background Chondroblastoma (CBL) is a rare benign chondroid producing bone tumor that typically occurs in epiphysis or apophysis of growing children and young adults. Intralesional curettage is the treatment of choice, while resection is required in selected cases, even though the use of mi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-02-01
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| Series: | BMC Musculoskeletal Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12891-023-06239-7 |
| _version_ | 1827979688698445824 |
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| author | Francesco Muratori Roberto Scanferla Giuliana Roselli Filippo Frenos Domenico Andrea Campanacci |
| author_facet | Francesco Muratori Roberto Scanferla Giuliana Roselli Filippo Frenos Domenico Andrea Campanacci |
| author_sort | Francesco Muratori |
| collection | DOAJ |
| description | Abstract Background Chondroblastoma (CBL) is a rare benign chondroid producing bone tumor that typically occurs in epiphysis or apophysis of growing children and young adults. Intralesional curettage is the treatment of choice, while resection is required in selected cases, even though the use of minimally invasive ablation techniques has been advocated. Authors reviewed a series of 75 CBLs with the aim of assess risk factors for local recurrence, the growth plate related complications after epiphyseal curettage and the risk of arthritis of the adjacent joint after epiphyseal curettage. Methods We retrospectively review 69 CBLs treated with intralesional curettage and 6 treated with resection from March 1995 to February 2020. The median age was 18.8 years (7 to 42, median 16). The site was proximal humerus in 18 cases, proximal tibia in 17, distal femur in 16, talus in 6, femur’s head in 4, calcaneus in 3, acromion in 3, trochanteric region in 2, distal tibia in 2, patella in 2, supracetabular region in 1 and distal humerus in 1 patient. Results Mean follow-up was 124.2 months (24 to 322, median 116). Among patients treated with curettage, 7.3% of local recurrence was observed and 12 (17.4%) patients developed osteoarthritis of the adjacent joint. Five patients (7.3%) presented limb length discrepancy of the operated limb ranging from 0.5 to 2 cm. Recurrence free survival rate was 94.2% at 5 and 91.6% at 10 years. A mean Musculoskeletal Tumor Society (MSTS) of 29.3 points (20 to 30, median 30) was observed. Conclusion More than 90% of CBLs were successfully treated with aggressive curettage but segmental resection is required in selected cases. In a relatively small proportion of cases long term complications can occur due to growth plate damage or osteoarthritis. Trial Registration Retrospectively registered. |
| first_indexed | 2024-04-09T21:40:44Z |
| format | Article |
| id | doaj.art-f287ec7944a546669a97185228cae836 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-04-09T21:40:44Z |
| publishDate | 2023-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-f287ec7944a546669a97185228cae8362023-03-26T11:03:11ZengBMCBMC Musculoskeletal Disorders1471-24742023-02-0124111110.1186/s12891-023-06239-7Long term outcome of surgical treatment of chondroblastoma: analysis of local control and growth plate/articular cartilage related complicationsFrancesco Muratori0Roberto Scanferla1Giuliana Roselli2Filippo Frenos3Domenico Andrea Campanacci4Department of Orthopaedic Oncology and Reconstructive Surgery, AOU CareggiDepartment of Radiology, AOU CareggiDepartment of Radiology, AOU CareggiDepartment of Orthopaedic Oncology and Reconstructive Surgery, AOU CareggiDepartment of Orthopaedic Oncology and Reconstructive Surgery, AOU CareggiAbstract Background Chondroblastoma (CBL) is a rare benign chondroid producing bone tumor that typically occurs in epiphysis or apophysis of growing children and young adults. Intralesional curettage is the treatment of choice, while resection is required in selected cases, even though the use of minimally invasive ablation techniques has been advocated. Authors reviewed a series of 75 CBLs with the aim of assess risk factors for local recurrence, the growth plate related complications after epiphyseal curettage and the risk of arthritis of the adjacent joint after epiphyseal curettage. Methods We retrospectively review 69 CBLs treated with intralesional curettage and 6 treated with resection from March 1995 to February 2020. The median age was 18.8 years (7 to 42, median 16). The site was proximal humerus in 18 cases, proximal tibia in 17, distal femur in 16, talus in 6, femur’s head in 4, calcaneus in 3, acromion in 3, trochanteric region in 2, distal tibia in 2, patella in 2, supracetabular region in 1 and distal humerus in 1 patient. Results Mean follow-up was 124.2 months (24 to 322, median 116). Among patients treated with curettage, 7.3% of local recurrence was observed and 12 (17.4%) patients developed osteoarthritis of the adjacent joint. Five patients (7.3%) presented limb length discrepancy of the operated limb ranging from 0.5 to 2 cm. Recurrence free survival rate was 94.2% at 5 and 91.6% at 10 years. A mean Musculoskeletal Tumor Society (MSTS) of 29.3 points (20 to 30, median 30) was observed. Conclusion More than 90% of CBLs were successfully treated with aggressive curettage but segmental resection is required in selected cases. In a relatively small proportion of cases long term complications can occur due to growth plate damage or osteoarthritis. Trial Registration Retrospectively registered.https://doi.org/10.1186/s12891-023-06239-7ChondroblastomaEpiphysisAggressive curettageRecurrenceOsteoarthritis |
| spellingShingle | Francesco Muratori Roberto Scanferla Giuliana Roselli Filippo Frenos Domenico Andrea Campanacci Long term outcome of surgical treatment of chondroblastoma: analysis of local control and growth plate/articular cartilage related complications BMC Musculoskeletal Disorders Chondroblastoma Epiphysis Aggressive curettage Recurrence Osteoarthritis |
| title | Long term outcome of surgical treatment of chondroblastoma: analysis of local control and growth plate/articular cartilage related complications |
| title_full | Long term outcome of surgical treatment of chondroblastoma: analysis of local control and growth plate/articular cartilage related complications |
| title_fullStr | Long term outcome of surgical treatment of chondroblastoma: analysis of local control and growth plate/articular cartilage related complications |
| title_full_unstemmed | Long term outcome of surgical treatment of chondroblastoma: analysis of local control and growth plate/articular cartilage related complications |
| title_short | Long term outcome of surgical treatment of chondroblastoma: analysis of local control and growth plate/articular cartilage related complications |
| title_sort | long term outcome of surgical treatment of chondroblastoma analysis of local control and growth plate articular cartilage related complications |
| topic | Chondroblastoma Epiphysis Aggressive curettage Recurrence Osteoarthritis |
| url | https://doi.org/10.1186/s12891-023-06239-7 |
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