Imbalance of Wnt/Dkk negative feedback promotes persistent activation of pancreatic stellate cells in chronic pancreatitis.

Imbalance of Wnt/Dkk negative feedback promotes persistent activation of pancreatic stellate cells in chronic pancreatitis.

The role of persistent activation of pancreatic stellate cells (PSCs) in the fibrosis associated with chronic pancreatitis (CP) is increasingly being recognized. Recent studies have shown that Wnt signaling is involved in the development of fibrosis in multiple organs, however, the role of specific...

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Bibliographic Details
Main Authors: Yanling Hu, Rong Wan, Ge Yu, Jie Shen, Jianbo Ni, Guojian Yin, Miao Xing, Congying Chen, Yuting Fan, Wenqin Xiao, Gang Xu, Xingpeng Wang, Guoyong Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3991593?pdf=render

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