Anxiety and depression in inherited channelopathy patients with implantable cardioverter-defibrillators
Background: Implantable cardioverter-defibrillators (ICDs) are an effective treatment in some patients with inherited heart disease, including inherited channelopathies, yet they have also been shown to impact patients’ psychological health. Objective: We sought to improve understanding of the level...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-08-01
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| Series: | Heart Rhythm O2 |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666501821001100 |
| _version_ | 1819108048490201088 |
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| author | Sajya M. Singh, BS Brittney Murray, MS, CGC Crystal Tichnell, MGC Rebecca McClellan, CGC, MGC Cynthia A. James, PhD, CGC Andreas S. Barth, MD, PhD |
| author_facet | Sajya M. Singh, BS Brittney Murray, MS, CGC Crystal Tichnell, MGC Rebecca McClellan, CGC, MGC Cynthia A. James, PhD, CGC Andreas S. Barth, MD, PhD |
| author_sort | Sajya M. Singh, BS |
| collection | DOAJ |
| description | Background: Implantable cardioverter-defibrillators (ICDs) are an effective treatment in some patients with inherited heart disease, including inherited channelopathies, yet they have also been shown to impact patients’ psychological health. Objective: We sought to improve understanding of the level of anxiety and depression as well as device acceptance among inherited channelopathy patients with an ICD. Methods: Eligible patients seen at Johns Hopkins Hospital were sent a survey, which included the Hospital Anxiety and Depression Scale (HADS), Cardiac Anxiety Questionnaire (CAQ), and the Florida Patient Acceptance Survey (FPAS). Student t tests and χ2 tests were used to identify associations with abnormal anxiety and depression scores. Results: Among eligible patients (n = 65), 32 individuals (49%) completed the survey. The rate of device-related complications was 34%, and 41% of patients experienced 1 or more ICD shocks. Twelve patients (38%) had an abnormal HADS anxiety subscore and 5 patients (16%) had an abnormal HADS depression subscore (score ≥ 8). Secondary-prevention ICDs were associated with an abnormal HADS anxiety subscore (P = .03). Experiencing ICD shock(s), device complications, age, sex, and family history of sudden cardiac death were not statistically associated with anxiety or depression. Overall, respondents demonstrated high device acceptance by FPAS (79.9 ± 2.9, maximum total score 100) and moderately high cardiac-specific anxiety by CAQ total score (1.53 ± 0.12). Conclusion: A high prevalence of generalized anxiety was identified among inherited channelopathy patients with ICDs. High device acceptance and lack of association with ICD shocks or complications indicate that further research is necessary to understand this increased incidence. |
| first_indexed | 2024-12-22T03:03:44Z |
| format | Article |
| id | doaj.art-f28acb51467f4f43bf6531fcd5ae95ca |
| institution | Directory Open Access Journal |
| issn | 2666-5018 |
| language | English |
| last_indexed | 2024-12-22T03:03:44Z |
| publishDate | 2021-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heart Rhythm O2 |
| spelling | doaj.art-f28acb51467f4f43bf6531fcd5ae95ca2022-12-21T18:41:07ZengElsevierHeart Rhythm O22666-50182021-08-0124388393Anxiety and depression in inherited channelopathy patients with implantable cardioverter-defibrillatorsSajya M. Singh, BS0Brittney Murray, MS, CGC1Crystal Tichnell, MGC2Rebecca McClellan, CGC, MGC3Cynthia A. James, PhD, CGC4Andreas S. Barth, MD, PhD5Johns Hopkins University School of Medicine, Baltimore, Maryland; Address reprint requests and correspondence: Ms. Sajya Singh, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Building 871, Baltimore, MD 21205.Department of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MarylandDepartment of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MarylandDepartment of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MarylandDepartment of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MarylandDepartment of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MarylandBackground: Implantable cardioverter-defibrillators (ICDs) are an effective treatment in some patients with inherited heart disease, including inherited channelopathies, yet they have also been shown to impact patients’ psychological health. Objective: We sought to improve understanding of the level of anxiety and depression as well as device acceptance among inherited channelopathy patients with an ICD. Methods: Eligible patients seen at Johns Hopkins Hospital were sent a survey, which included the Hospital Anxiety and Depression Scale (HADS), Cardiac Anxiety Questionnaire (CAQ), and the Florida Patient Acceptance Survey (FPAS). Student t tests and χ2 tests were used to identify associations with abnormal anxiety and depression scores. Results: Among eligible patients (n = 65), 32 individuals (49%) completed the survey. The rate of device-related complications was 34%, and 41% of patients experienced 1 or more ICD shocks. Twelve patients (38%) had an abnormal HADS anxiety subscore and 5 patients (16%) had an abnormal HADS depression subscore (score ≥ 8). Secondary-prevention ICDs were associated with an abnormal HADS anxiety subscore (P = .03). Experiencing ICD shock(s), device complications, age, sex, and family history of sudden cardiac death were not statistically associated with anxiety or depression. Overall, respondents demonstrated high device acceptance by FPAS (79.9 ± 2.9, maximum total score 100) and moderately high cardiac-specific anxiety by CAQ total score (1.53 ± 0.12). Conclusion: A high prevalence of generalized anxiety was identified among inherited channelopathy patients with ICDs. High device acceptance and lack of association with ICD shocks or complications indicate that further research is necessary to understand this increased incidence.http://www.sciencedirect.com/science/article/pii/S2666501821001100AnxietyBrugada syndromeCardiac electrophysiologyDepressionImplantable cardioverter-defibrillator (ICD)Inherited heart disease |
| spellingShingle | Sajya M. Singh, BS Brittney Murray, MS, CGC Crystal Tichnell, MGC Rebecca McClellan, CGC, MGC Cynthia A. James, PhD, CGC Andreas S. Barth, MD, PhD Anxiety and depression in inherited channelopathy patients with implantable cardioverter-defibrillators Heart Rhythm O2 Anxiety Brugada syndrome Cardiac electrophysiology Depression Implantable cardioverter-defibrillator (ICD) Inherited heart disease |
| title | Anxiety and depression in inherited channelopathy patients with implantable cardioverter-defibrillators |
| title_full | Anxiety and depression in inherited channelopathy patients with implantable cardioverter-defibrillators |
| title_fullStr | Anxiety and depression in inherited channelopathy patients with implantable cardioverter-defibrillators |
| title_full_unstemmed | Anxiety and depression in inherited channelopathy patients with implantable cardioverter-defibrillators |
| title_short | Anxiety and depression in inherited channelopathy patients with implantable cardioverter-defibrillators |
| title_sort | anxiety and depression in inherited channelopathy patients with implantable cardioverter defibrillators |
| topic | Anxiety Brugada syndrome Cardiac electrophysiology Depression Implantable cardioverter-defibrillator (ICD) Inherited heart disease |
| url | http://www.sciencedirect.com/science/article/pii/S2666501821001100 |
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