Best therapeutic practices in the management of obstetric sepsis

Background. Physiological changes that occur during pregnancy make maternal sepsis a difficult condition to diagnose and treat, still having a fairly high mortality rate. Consequently, an early diagnosis and prompt therapeutic management of sepsis can significantly decrease mortality. The purpose of...

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Main Authors: Gabriel Petre Gorecki, Oana Denisa Balalau, Diana Elena Comandasu, Anca Daniela Stanescu, Dana Rodica Tomescu
Format: Article
Language:English
Published: Ion Motofei, Carol Davila University 2023-10-01
Series:Journal of Mind and Medical Sciences
Subjects:
Online Access:https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1436&context=jmms
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author Gabriel Petre Gorecki
Oana Denisa Balalau
Diana Elena Comandasu
Anca Daniela Stanescu
Dana Rodica Tomescu
author_facet Gabriel Petre Gorecki
Oana Denisa Balalau
Diana Elena Comandasu
Anca Daniela Stanescu
Dana Rodica Tomescu
author_sort Gabriel Petre Gorecki
collection DOAJ
description Background. Physiological changes that occur during pregnancy make maternal sepsis a difficult condition to diagnose and treat, still having a fairly high mortality rate. Consequently, an early diagnosis and prompt therapeutic management of sepsis can significantly decrease mortality. The purpose of this study is to review literature data that present current practices in the management of obstetric sepsis. Methods. To collect the data required for the study, we performed a search of published articles in the PubMed and Google Scholar databases related to obstetric sepsis. Research paper articles from the period 2012-2022 were included in the analysis. In addition, 145 articles from the period 2012-2022 were evaluated, with the aim of finding out in which situations the risk of maternal death is higher. Thus, the analysis included a total number of 151 articles, which were divided into two distinct stages. Results. The risk of maternal death is higher among patients with the human immunodeficiency virus (HIV), followed by Escherichia coli, genital tract infection, cancer, drug users and in the case of patients with chronic liver disease. Conclusions. After analyzing the data, we found that prompt and focused antibiotic therapy as well as fluid resuscitation are essential to increase the chances of survival of these patients.
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spelling doaj.art-f28bef03280242aba0a6bd529d671fbf2023-11-21T18:33:30ZengIon Motofei, Carol Davila UniversityJournal of Mind and Medical Sciences2392-76742023-10-0110230431110.22543/2392-7674.1436Best therapeutic practices in the management of obstetric sepsisGabriel Petre Gorecki0Oana Denisa Balalau1Diana Elena Comandasu2Anca Daniela Stanescu3Dana Rodica Tomescu4Titu Maiorescu University, Faculty of Medicine, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaBackground. Physiological changes that occur during pregnancy make maternal sepsis a difficult condition to diagnose and treat, still having a fairly high mortality rate. Consequently, an early diagnosis and prompt therapeutic management of sepsis can significantly decrease mortality. The purpose of this study is to review literature data that present current practices in the management of obstetric sepsis. Methods. To collect the data required for the study, we performed a search of published articles in the PubMed and Google Scholar databases related to obstetric sepsis. Research paper articles from the period 2012-2022 were included in the analysis. In addition, 145 articles from the period 2012-2022 were evaluated, with the aim of finding out in which situations the risk of maternal death is higher. Thus, the analysis included a total number of 151 articles, which were divided into two distinct stages. Results. The risk of maternal death is higher among patients with the human immunodeficiency virus (HIV), followed by Escherichia coli, genital tract infection, cancer, drug users and in the case of patients with chronic liver disease. Conclusions. After analyzing the data, we found that prompt and focused antibiotic therapy as well as fluid resuscitation are essential to increase the chances of survival of these patients.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1436&context=jmmsobstetric sepsismaternal sepsisseptic shocktherapybest practices
spellingShingle Gabriel Petre Gorecki
Oana Denisa Balalau
Diana Elena Comandasu
Anca Daniela Stanescu
Dana Rodica Tomescu
Best therapeutic practices in the management of obstetric sepsis
Journal of Mind and Medical Sciences
obstetric sepsis
maternal sepsis
septic shock
therapy
best practices
title Best therapeutic practices in the management of obstetric sepsis
title_full Best therapeutic practices in the management of obstetric sepsis
title_fullStr Best therapeutic practices in the management of obstetric sepsis
title_full_unstemmed Best therapeutic practices in the management of obstetric sepsis
title_short Best therapeutic practices in the management of obstetric sepsis
title_sort best therapeutic practices in the management of obstetric sepsis
topic obstetric sepsis
maternal sepsis
septic shock
therapy
best practices
url https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1436&context=jmms
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