Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic Treatment
Background: New antineoplastic agents have increased the survival rate of cancer patients, however, the incidence of cutaneous skin toxicity, which leads to worsening in the quality of life and to the necessity of interrupting the treatment, continues presently. Natural agents, as Aloe vera and Cale...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Oncologia Clínica, Sociedade Brasileira de Cirurgia Clínica and Sociedade Brasileira de Radioterapia
2021-10-01
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| Series: | Brazilian Journal of Oncology |
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| Online Access: | http://www.brazilianjournalofoncology.com.br/details/144/en-US/cutaneous-acceptability-and-hydratation-of-topical-products-in-patients-undergoing-radiotherapy-and-antineoplastic-treatment |
| _version_ | 1797673892734566400 |
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| author | Carlos D`App Santos Machado-Filho Odimila Kawahata Adriano Silva Silvia Regina Lamas |
| author_facet | Carlos D`App Santos Machado-Filho Odimila Kawahata Adriano Silva Silvia Regina Lamas |
| author_sort | Carlos D`App Santos Machado-Filho |
| collection | DOAJ |
| description | Background: New antineoplastic agents have increased the survival rate of cancer patients, however, the incidence of cutaneous skin toxicity, which leads to worsening in the quality of life and to the necessity of interrupting the treatment, continues presently. Natural agents, as Aloe vera and Calendula, have been suggested as potential ways of prevention and treatment for radiation dermatitis resulting from radiotherapy, providing better adhesion to the therapies and improving the wellbeing of the patients.
Purpose: To evaluate the cutaneous acceptability and hydrating effect of four topical test products in patients undergoing radiotherapy and antineoplastic treatment.
Methods: Both sex participants, undergoing oncological treatments, were included. Patients received a prescription to self-applied topical test products - A (Washcare), B (Moistcare), C (Extremecare) and D (Coolcare Mask) during 30 days. Products acceptability and skin hydration were evaluated considering the occurrence of skin adverse reaction, participants self-reported feelings of skin discomfort, dermatologist and instrumental skin hydration evaluation.
Results: Thirty-three participants initiated and completed the study. None of them had skin reactions or discomfort in the area of application, and no adverse events were reported. Twenty-five participants (75.8%) reported improvement in skin hydration after using the test products, while eight participants (24.2%) observed the maintenance of hydration (p<0,005).
Conclusion: The products evaluated showed improvement in skin condition in most patients, increased hydration and good skin acceptability in patients with skin toxicities caused by the cancer treatments. |
| first_indexed | 2024-03-11T21:51:59Z |
| format | Article |
| id | doaj.art-f290218923a74e65b87cbc972879bc91 |
| institution | Directory Open Access Journal |
| issn | 2526-8732 |
| language | English |
| last_indexed | 2024-03-11T21:51:59Z |
| publishDate | 2021-10-01 |
| publisher | Sociedade Brasileira de Oncologia Clínica, Sociedade Brasileira de Cirurgia Clínica and Sociedade Brasileira de Radioterapia |
| record_format | Article |
| series | Brazilian Journal of Oncology |
| spelling | doaj.art-f290218923a74e65b87cbc972879bc912023-09-26T09:00:16ZengSociedade Brasileira de Oncologia Clínica, Sociedade Brasileira de Cirurgia Clínica and Sociedade Brasileira de RadioterapiaBrazilian Journal of Oncology2526-87322021-10-01170010.5935/2526-8732.20210005Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic TreatmentCarlos D`App Santos Machado-Filho0Odimila Kawahata Adriano Silva1Silvia Regina Lamas2Faculdade de Medicina do ABC, Dermatology - Sao Paulo - SP - BrazilCentro de Estudos Kenji Toyoda, Dermatology - Santo Andre - SP - BrazilUniversidade Anhanguera de São Paulo, Medicine - Sao Paulo - SP - BrazilBackground: New antineoplastic agents have increased the survival rate of cancer patients, however, the incidence of cutaneous skin toxicity, which leads to worsening in the quality of life and to the necessity of interrupting the treatment, continues presently. Natural agents, as Aloe vera and Calendula, have been suggested as potential ways of prevention and treatment for radiation dermatitis resulting from radiotherapy, providing better adhesion to the therapies and improving the wellbeing of the patients. Purpose: To evaluate the cutaneous acceptability and hydrating effect of four topical test products in patients undergoing radiotherapy and antineoplastic treatment. Methods: Both sex participants, undergoing oncological treatments, were included. Patients received a prescription to self-applied topical test products - A (Washcare), B (Moistcare), C (Extremecare) and D (Coolcare Mask) during 30 days. Products acceptability and skin hydration were evaluated considering the occurrence of skin adverse reaction, participants self-reported feelings of skin discomfort, dermatologist and instrumental skin hydration evaluation. Results: Thirty-three participants initiated and completed the study. None of them had skin reactions or discomfort in the area of application, and no adverse events were reported. Twenty-five participants (75.8%) reported improvement in skin hydration after using the test products, while eight participants (24.2%) observed the maintenance of hydration (p<0,005). Conclusion: The products evaluated showed improvement in skin condition in most patients, increased hydration and good skin acceptability in patients with skin toxicities caused by the cancer treatments.http://www.brazilianjournalofoncology.com.br/details/144/en-US/cutaneous-acceptability-and-hydratation-of-topical-products-in-patients-undergoing-radiotherapy-and-antineoplastic-treatmentcalendularadiodermatitisaloewounds and injuriesskintoxicity |
| spellingShingle | Carlos D`App Santos Machado-Filho Odimila Kawahata Adriano Silva Silvia Regina Lamas Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic Treatment Brazilian Journal of Oncology calendula radiodermatitis aloe wounds and injuries skin toxicity |
| title | Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic Treatment |
| title_full | Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic Treatment |
| title_fullStr | Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic Treatment |
| title_full_unstemmed | Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic Treatment |
| title_short | Cutaneous Acceptability And Hydratation of Topical Products In Patients Undergoing Radiotherapy and Antineoplastic Treatment |
| title_sort | cutaneous acceptability and hydratation of topical products in patients undergoing radiotherapy and antineoplastic treatment |
| topic | calendula radiodermatitis aloe wounds and injuries skin toxicity |
| url | http://www.brazilianjournalofoncology.com.br/details/144/en-US/cutaneous-acceptability-and-hydratation-of-topical-products-in-patients-undergoing-radiotherapy-and-antineoplastic-treatment |
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