Microvesicles shed from fibroblasts act as metalloproteinase carriers in a 3-D collagen matrix
This study shows that fibroblasts migrating into a collagen matrix release numerous microvesicles into the surrounding medium. By spreading in regions of the matrix far distant from cells of origin, microvesicles carry metalloproteinase 9 (MMP-9) to act upon the collagen fibrils. As a result, the co...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AboutScience Srl
2016-11-01
|
| Series: | Journal of Circulating Biomarkers |
| Online Access: | https://doi.org/10.1177/1849454416663660 |