Day-of-the-week variation of sudden unexpected cardiac death

Background: There has been some controversy about the day-of-the-week (septadian) variation of unexpected sudden cardiac death (SCD). Methods: We evaluated the incidence of unexpected SCD on different days of the week in a consecutive series of 5869 SCD victims from Northern Finland [the FINGESTURE...

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Main Authors: Hanna Latola, Severi M. Mattila, Lasse Pakanen, Lauri Holmström, Janna Kauppila, Olavi H. Ukkola, M Juhani Junttila, Heikki V. Huikuri, Juha S. Perkiömäki
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:International Journal of Cardiology. Cardiovascular Risk and Prevention
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772487524000114
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author Hanna Latola
Severi M. Mattila
Lasse Pakanen
Lauri Holmström
Janna Kauppila
Olavi H. Ukkola
M Juhani Junttila
Heikki V. Huikuri
Juha S. Perkiömäki
author_facet Hanna Latola
Severi M. Mattila
Lasse Pakanen
Lauri Holmström
Janna Kauppila
Olavi H. Ukkola
M Juhani Junttila
Heikki V. Huikuri
Juha S. Perkiömäki
author_sort Hanna Latola
collection DOAJ
description Background: There has been some controversy about the day-of-the-week (septadian) variation of unexpected sudden cardiac death (SCD). Methods: We evaluated the incidence of unexpected SCD on different days of the week in a consecutive series of 5869 SCD victims from Northern Finland [the FINGESTURE study (Finnish Genetic Study of Arrhythmic Events)]. As it is mandatory in Finland, a medico-legal autopsy was performed on all unexpected sudden death victims. The autopsies were performed between the years 1998–2017. Results: The mean incidence of unexpected SCD was higher at weekends (during the days from Friday to Sunday, peaking on Saturday) than during the days from Monday to Thursday (8.54 ± 0.72 vs. 7.22 ± 0.19 SCDs per day of the week per 100,000 inhabitants per year, p < 0.001). Regardless of sex or ischemic versus non-ischemic etiology of SCD, the distribution of the occurrence of SCD among the days of the week was similar compared with the whole SCD cohort. Conclusion: The incidence of unexpected SCD was highest at weekends (during the days from Friday to Sunday, peaking on Saturday).
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spelling doaj.art-f294c4641cad4e97a864068c0ef344fa2024-03-06T05:29:08ZengElsevierInternational Journal of Cardiology. Cardiovascular Risk and Prevention2772-48752024-03-0120200246Day-of-the-week variation of sudden unexpected cardiac deathHanna Latola0Severi M. Mattila1Lasse Pakanen2Lauri Holmström3Janna Kauppila4Olavi H. Ukkola5M Juhani Junttila6Heikki V. Huikuri7Juha S. Perkiömäki8Research Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, FinlandResearch Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, FinlandForensic Medicine Unit, Finnish Institute for Health and Welfare, Oulu, Finland; Department of Forensic Medicine, Research Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu, Oulu, FinlandResearch Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, FinlandResearch Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, FinlandResearch Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, FinlandResearch Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, FinlandResearch Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, FinlandResearch Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland; Corresponding author. Division of Cardiology, Medical Research Center Oulu, University of Oulu, P.O. Box 5000, Kajaanintie 50, FIN-90014, Oulu, Finland.Background: There has been some controversy about the day-of-the-week (septadian) variation of unexpected sudden cardiac death (SCD). Methods: We evaluated the incidence of unexpected SCD on different days of the week in a consecutive series of 5869 SCD victims from Northern Finland [the FINGESTURE study (Finnish Genetic Study of Arrhythmic Events)]. As it is mandatory in Finland, a medico-legal autopsy was performed on all unexpected sudden death victims. The autopsies were performed between the years 1998–2017. Results: The mean incidence of unexpected SCD was higher at weekends (during the days from Friday to Sunday, peaking on Saturday) than during the days from Monday to Thursday (8.54 ± 0.72 vs. 7.22 ± 0.19 SCDs per day of the week per 100,000 inhabitants per year, p < 0.001). Regardless of sex or ischemic versus non-ischemic etiology of SCD, the distribution of the occurrence of SCD among the days of the week was similar compared with the whole SCD cohort. Conclusion: The incidence of unexpected SCD was highest at weekends (during the days from Friday to Sunday, peaking on Saturday).http://www.sciencedirect.com/science/article/pii/S2772487524000114Sudden cardiac deathSeptadian variationMedico-legal autopsy
spellingShingle Hanna Latola
Severi M. Mattila
Lasse Pakanen
Lauri Holmström
Janna Kauppila
Olavi H. Ukkola
M Juhani Junttila
Heikki V. Huikuri
Juha S. Perkiömäki
Day-of-the-week variation of sudden unexpected cardiac death
International Journal of Cardiology. Cardiovascular Risk and Prevention
Sudden cardiac death
Septadian variation
Medico-legal autopsy
title Day-of-the-week variation of sudden unexpected cardiac death
title_full Day-of-the-week variation of sudden unexpected cardiac death
title_fullStr Day-of-the-week variation of sudden unexpected cardiac death
title_full_unstemmed Day-of-the-week variation of sudden unexpected cardiac death
title_short Day-of-the-week variation of sudden unexpected cardiac death
title_sort day of the week variation of sudden unexpected cardiac death
topic Sudden cardiac death
Septadian variation
Medico-legal autopsy
url http://www.sciencedirect.com/science/article/pii/S2772487524000114
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AT jannakauppila dayoftheweekvariationofsuddenunexpectedcardiacdeath
AT olavihukkola dayoftheweekvariationofsuddenunexpectedcardiacdeath
AT mjuhanijunttila dayoftheweekvariationofsuddenunexpectedcardiacdeath
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