Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation

Background: The purpose of this study is to estimate the success rate of subliminal transscleral cyclophotocoagulation for refractory glaucoma and to determine the correlation between the decrease in intraocular pressure and the variation in choroidal thickness. Methods: A pre–post study was conduct...

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Main Authors: Florian Baltă, Valentin Dinu, Mihail Zemba, George Baltă, Andreea Diana Barac, Speranța Schmitzer, Christiana Diana Maria Dragosloveanu, Ramona Ileana Barac
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/12/7/1513
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author Florian Baltă
Valentin Dinu
Mihail Zemba
George Baltă
Andreea Diana Barac
Speranța Schmitzer
Christiana Diana Maria Dragosloveanu
Ramona Ileana Barac
author_facet Florian Baltă
Valentin Dinu
Mihail Zemba
George Baltă
Andreea Diana Barac
Speranța Schmitzer
Christiana Diana Maria Dragosloveanu
Ramona Ileana Barac
author_sort Florian Baltă
collection DOAJ
description Background: The purpose of this study is to estimate the success rate of subliminal transscleral cyclophotocoagulation for refractory glaucoma and to determine the correlation between the decrease in intraocular pressure and the variation in choroidal thickness. Methods: A pre–post study was conducted over a period of 3 years, including 81 eyes from 67 patients with different types of drug-refractory glaucoma who underwent subliminal transscleral cyclophotocoagulation. The variables included best-corrected visual acuity, intraocular pressure and choroidal thickness. Results: We observed the following success rates (defined as IOP < 21 mmHg): 80% at 1 month (65 patients), 74% at 3 months (60 patients), 64% at 6 months (52 patients) and 50.6% at 1 year (41 patients). A strong correlation was noted between the decrease in intraocular pressure and the increase in the average choroidal thickness at 1 year (318.42 µm) compared to the average preoperative thickness (291.78 µm). A correlation of increased choroidal thickness at 1-month with the success rate of the procedure was also observed. Conclusions: We observed a statistically significant correlation between the success rate, decrease in intraocular pressure and choroidal thickness. The correlation of increased choroidal thickness at 1-month with the success rate of the procedure could be used clinically as a predictive factor for the final outcome of patients. Further experimental research is warranted to determine whether the increase in choroidal thickness after subliminal transscleral cyclophotocoagulation is indeed evidence of increased uveoscleral drainage.
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spelling doaj.art-f294ebfbb1454d488ae8a0afe81737922023-12-03T14:53:23ZengMDPI AGDiagnostics2075-44182022-06-01127151310.3390/diagnostics12071513Choroidal Thickness Increase after Subliminal Transscleral CyclophotocoagulationFlorian Baltă0Valentin Dinu1Mihail Zemba2George Baltă3Andreea Diana Barac4Speranța Schmitzer5Christiana Diana Maria Dragosloveanu6Ramona Ileana Barac7Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaBucharest Emergency Eye Hospital, 030167 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaBackground: The purpose of this study is to estimate the success rate of subliminal transscleral cyclophotocoagulation for refractory glaucoma and to determine the correlation between the decrease in intraocular pressure and the variation in choroidal thickness. Methods: A pre–post study was conducted over a period of 3 years, including 81 eyes from 67 patients with different types of drug-refractory glaucoma who underwent subliminal transscleral cyclophotocoagulation. The variables included best-corrected visual acuity, intraocular pressure and choroidal thickness. Results: We observed the following success rates (defined as IOP < 21 mmHg): 80% at 1 month (65 patients), 74% at 3 months (60 patients), 64% at 6 months (52 patients) and 50.6% at 1 year (41 patients). A strong correlation was noted between the decrease in intraocular pressure and the increase in the average choroidal thickness at 1 year (318.42 µm) compared to the average preoperative thickness (291.78 µm). A correlation of increased choroidal thickness at 1-month with the success rate of the procedure was also observed. Conclusions: We observed a statistically significant correlation between the success rate, decrease in intraocular pressure and choroidal thickness. The correlation of increased choroidal thickness at 1-month with the success rate of the procedure could be used clinically as a predictive factor for the final outcome of patients. Further experimental research is warranted to determine whether the increase in choroidal thickness after subliminal transscleral cyclophotocoagulation is indeed evidence of increased uveoscleral drainage.https://www.mdpi.com/2075-4418/12/7/1513subliminal transscleral cyclophotocoagulationchoroidal thicknessintraocular pressure
spellingShingle Florian Baltă
Valentin Dinu
Mihail Zemba
George Baltă
Andreea Diana Barac
Speranța Schmitzer
Christiana Diana Maria Dragosloveanu
Ramona Ileana Barac
Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
Diagnostics
subliminal transscleral cyclophotocoagulation
choroidal thickness
intraocular pressure
title Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_full Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_fullStr Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_full_unstemmed Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_short Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
title_sort choroidal thickness increase after subliminal transscleral cyclophotocoagulation
topic subliminal transscleral cyclophotocoagulation
choroidal thickness
intraocular pressure
url https://www.mdpi.com/2075-4418/12/7/1513
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