Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation
Background: The purpose of this study is to estimate the success rate of subliminal transscleral cyclophotocoagulation for refractory glaucoma and to determine the correlation between the decrease in intraocular pressure and the variation in choroidal thickness. Methods: A pre–post study was conduct...
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MDPI AG
2022-06-01
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author | Florian Baltă Valentin Dinu Mihail Zemba George Baltă Andreea Diana Barac Speranța Schmitzer Christiana Diana Maria Dragosloveanu Ramona Ileana Barac |
author_facet | Florian Baltă Valentin Dinu Mihail Zemba George Baltă Andreea Diana Barac Speranța Schmitzer Christiana Diana Maria Dragosloveanu Ramona Ileana Barac |
author_sort | Florian Baltă |
collection | DOAJ |
description | Background: The purpose of this study is to estimate the success rate of subliminal transscleral cyclophotocoagulation for refractory glaucoma and to determine the correlation between the decrease in intraocular pressure and the variation in choroidal thickness. Methods: A pre–post study was conducted over a period of 3 years, including 81 eyes from 67 patients with different types of drug-refractory glaucoma who underwent subliminal transscleral cyclophotocoagulation. The variables included best-corrected visual acuity, intraocular pressure and choroidal thickness. Results: We observed the following success rates (defined as IOP < 21 mmHg): 80% at 1 month (65 patients), 74% at 3 months (60 patients), 64% at 6 months (52 patients) and 50.6% at 1 year (41 patients). A strong correlation was noted between the decrease in intraocular pressure and the increase in the average choroidal thickness at 1 year (318.42 µm) compared to the average preoperative thickness (291.78 µm). A correlation of increased choroidal thickness at 1-month with the success rate of the procedure was also observed. Conclusions: We observed a statistically significant correlation between the success rate, decrease in intraocular pressure and choroidal thickness. The correlation of increased choroidal thickness at 1-month with the success rate of the procedure could be used clinically as a predictive factor for the final outcome of patients. Further experimental research is warranted to determine whether the increase in choroidal thickness after subliminal transscleral cyclophotocoagulation is indeed evidence of increased uveoscleral drainage. |
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spelling | doaj.art-f294ebfbb1454d488ae8a0afe81737922023-12-03T14:53:23ZengMDPI AGDiagnostics2075-44182022-06-01127151310.3390/diagnostics12071513Choroidal Thickness Increase after Subliminal Transscleral CyclophotocoagulationFlorian Baltă0Valentin Dinu1Mihail Zemba2George Baltă3Andreea Diana Barac4Speranța Schmitzer5Christiana Diana Maria Dragosloveanu6Ramona Ileana Barac7Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaBucharest Emergency Eye Hospital, 030167 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaBackground: The purpose of this study is to estimate the success rate of subliminal transscleral cyclophotocoagulation for refractory glaucoma and to determine the correlation between the decrease in intraocular pressure and the variation in choroidal thickness. Methods: A pre–post study was conducted over a period of 3 years, including 81 eyes from 67 patients with different types of drug-refractory glaucoma who underwent subliminal transscleral cyclophotocoagulation. The variables included best-corrected visual acuity, intraocular pressure and choroidal thickness. Results: We observed the following success rates (defined as IOP < 21 mmHg): 80% at 1 month (65 patients), 74% at 3 months (60 patients), 64% at 6 months (52 patients) and 50.6% at 1 year (41 patients). A strong correlation was noted between the decrease in intraocular pressure and the increase in the average choroidal thickness at 1 year (318.42 µm) compared to the average preoperative thickness (291.78 µm). A correlation of increased choroidal thickness at 1-month with the success rate of the procedure was also observed. Conclusions: We observed a statistically significant correlation between the success rate, decrease in intraocular pressure and choroidal thickness. The correlation of increased choroidal thickness at 1-month with the success rate of the procedure could be used clinically as a predictive factor for the final outcome of patients. Further experimental research is warranted to determine whether the increase in choroidal thickness after subliminal transscleral cyclophotocoagulation is indeed evidence of increased uveoscleral drainage.https://www.mdpi.com/2075-4418/12/7/1513subliminal transscleral cyclophotocoagulationchoroidal thicknessintraocular pressure |
spellingShingle | Florian Baltă Valentin Dinu Mihail Zemba George Baltă Andreea Diana Barac Speranța Schmitzer Christiana Diana Maria Dragosloveanu Ramona Ileana Barac Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation Diagnostics subliminal transscleral cyclophotocoagulation choroidal thickness intraocular pressure |
title | Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation |
title_full | Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation |
title_fullStr | Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation |
title_full_unstemmed | Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation |
title_short | Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation |
title_sort | choroidal thickness increase after subliminal transscleral cyclophotocoagulation |
topic | subliminal transscleral cyclophotocoagulation choroidal thickness intraocular pressure |
url | https://www.mdpi.com/2075-4418/12/7/1513 |
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