High Expression of MRE11A Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients

High Expression of MRE11A Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients

Background: Homologous recombination repair (HR) is the most accurate repair pathway for double-strand breaks and replication fork disruption that is capable of faithfully restoring the original nucleotide sequence of the broken DNA. The deficiency of this mechanism is a frequent event in tumorigene...

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Bibliographic Details
Main Authors: Daniel de Barcellos Azambuja, Helena de Castro e Gloria, Gabriel e Silva Montenegro, Antonio Nocchi Kalil, Jean-Sébastien Hoffmann, Natalia Motta Leguisamo, Jenifer Saffi
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Genes
Subjects:
colorectal cancer
homologous recombination
prognosis
MRE11
Online Access:https://www.mdpi.com/2073-4425/14/6/1270

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