Effects of a false-positive result in newborn congenital hypothyroidism screening on parents in Guangxi, China
BackgroundAs more than 500,000 neonates participate in newborn congenital hypothyroidism (CH) screening in Guangxi Zhuang Autonomous Region each year, the overall number of false-positive (FP) cases has increased. We aim to assess the parental stress in parents of neonates with FP CH results in Guan...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2023.1134923/full |
| _version_ | 1797828903949041664 |
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| author | Si-Jing Tu Si-Jing Tu Yu-Jia Wei Bu-Tong Chen Xiao-Fei Zhang Chao Luo Bai-Qing Dong |
| author_facet | Si-Jing Tu Si-Jing Tu Yu-Jia Wei Bu-Tong Chen Xiao-Fei Zhang Chao Luo Bai-Qing Dong |
| author_sort | Si-Jing Tu |
| collection | DOAJ |
| description | BackgroundAs more than 500,000 neonates participate in newborn congenital hypothyroidism (CH) screening in Guangxi Zhuang Autonomous Region each year, the overall number of false-positive (FP) cases has increased. We aim to assess the parental stress in parents of neonates with FP CH results in Guangxi, find out the influence factors related to demographics, and provide the basis for personalized health education.MethodsThe parents of neonates with FP CH results were invited to participate in the FP group, and the parents of neonates with all negative results were invited to participate in the control group. The parents completed a questionnaire on demographics, knowledge of CH, and the parental stress index (PSI) in the hospital for the first time. The follow-up visits for PSI were conducted 3, 6, and 12 months afterward through telephone and online.ResultsA total of 258 and 1,040 parents participated in the FP and control groups, respectively. The parents in the FP group had better knowledge of CH and higher PSI scores than the parents in the control group. The result of logistic regression showed that the major influence factors related to the knowledge of CH were FP experience and source of knowledge. The parents in the FP group who were well-informed during the recall phone call had lower PSI scores than the other parents. The parents in the FP group showed decreasing PSI scores gradually in follow-up visits.ConclusionThe results suggested that FP screening results may affect parental stress and parent–child relationship. FP results increased the stress on the parents and increased their knowledge of CH passively. |
| first_indexed | 2024-04-09T13:11:53Z |
| format | Article |
| id | doaj.art-f29a8e49a2724276a9b628ee38e64378 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-09T13:11:53Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-f29a8e49a2724276a9b628ee38e643782023-05-12T07:05:25ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-05-011110.3389/fped.2023.11349231134923Effects of a false-positive result in newborn congenital hypothyroidism screening on parents in Guangxi, ChinaSi-Jing Tu0Si-Jing Tu1Yu-Jia Wei2Bu-Tong Chen3Xiao-Fei Zhang4Chao Luo5Bai-Qing Dong6School of Public Health and Management, Guangxi University of Chinese Medicine, Nanning, ChinaSchool of Public Health, Hangzhou Normal University, Hangzhou, ChinaSchool of Public Health and Management, Guangxi University of Chinese Medicine, Nanning, ChinaSchool of Humanities and Social Sciences, Guangxi Medical University, Nanning, ChinaDepartment of Pediatrics, The Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning, ChinaShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaSchool of Public Health and Management, Guangxi University of Chinese Medicine, Nanning, ChinaBackgroundAs more than 500,000 neonates participate in newborn congenital hypothyroidism (CH) screening in Guangxi Zhuang Autonomous Region each year, the overall number of false-positive (FP) cases has increased. We aim to assess the parental stress in parents of neonates with FP CH results in Guangxi, find out the influence factors related to demographics, and provide the basis for personalized health education.MethodsThe parents of neonates with FP CH results were invited to participate in the FP group, and the parents of neonates with all negative results were invited to participate in the control group. The parents completed a questionnaire on demographics, knowledge of CH, and the parental stress index (PSI) in the hospital for the first time. The follow-up visits for PSI were conducted 3, 6, and 12 months afterward through telephone and online.ResultsA total of 258 and 1,040 parents participated in the FP and control groups, respectively. The parents in the FP group had better knowledge of CH and higher PSI scores than the parents in the control group. The result of logistic regression showed that the major influence factors related to the knowledge of CH were FP experience and source of knowledge. The parents in the FP group who were well-informed during the recall phone call had lower PSI scores than the other parents. The parents in the FP group showed decreasing PSI scores gradually in follow-up visits.ConclusionThe results suggested that FP screening results may affect parental stress and parent–child relationship. FP results increased the stress on the parents and increased their knowledge of CH passively.https://www.frontiersin.org/articles/10.3389/fped.2023.1134923/fullnewborn screeningfalse-positivecongenital hypothyroidismparenting stress indexhealth education |
| spellingShingle | Si-Jing Tu Si-Jing Tu Yu-Jia Wei Bu-Tong Chen Xiao-Fei Zhang Chao Luo Bai-Qing Dong Effects of a false-positive result in newborn congenital hypothyroidism screening on parents in Guangxi, China Frontiers in Pediatrics newborn screening false-positive congenital hypothyroidism parenting stress index health education |
| title | Effects of a false-positive result in newborn congenital hypothyroidism screening on parents in Guangxi, China |
| title_full | Effects of a false-positive result in newborn congenital hypothyroidism screening on parents in Guangxi, China |
| title_fullStr | Effects of a false-positive result in newborn congenital hypothyroidism screening on parents in Guangxi, China |
| title_full_unstemmed | Effects of a false-positive result in newborn congenital hypothyroidism screening on parents in Guangxi, China |
| title_short | Effects of a false-positive result in newborn congenital hypothyroidism screening on parents in Guangxi, China |
| title_sort | effects of a false positive result in newborn congenital hypothyroidism screening on parents in guangxi china |
| topic | newborn screening false-positive congenital hypothyroidism parenting stress index health education |
| url | https://www.frontiersin.org/articles/10.3389/fped.2023.1134923/full |
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