COVID-19-associated immune thrombocytopenia

The coronavirus disease 2019 (COVID-19) is a contagious respiratory tract infection caused by the betacoronavirus SARS-CoV-2. The World Health Organization declared the COVID-19 outbreak a pandemic on March 11, 2020. Since the COVID-19 pandemic started, more than 166 million patients have been teste...

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Main Authors: Mara-Andrada Plesu, Gabriel Cristian Bejan, Ioana Veronica Grajdeanu, Anca Angela Simionescu, Ana Maria Alexandra Stanescu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2021-06-01
Series:Romanian Journal of Infectious Diseases
Subjects:
Online Access:https://rjid.com.ro/articles/2021.2/RJID_2021_2_Art-01.pdf
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author Mara-Andrada Plesu
Gabriel Cristian Bejan
Ioana Veronica Grajdeanu
Anca Angela Simionescu
Ana Maria Alexandra Stanescu
author_facet Mara-Andrada Plesu
Gabriel Cristian Bejan
Ioana Veronica Grajdeanu
Anca Angela Simionescu
Ana Maria Alexandra Stanescu
author_sort Mara-Andrada Plesu
collection DOAJ
description The coronavirus disease 2019 (COVID-19) is a contagious respiratory tract infection caused by the betacoronavirus SARS-CoV-2. The World Health Organization declared the COVID-19 outbreak a pandemic on March 11, 2020. Since the COVID-19 pandemic started, more than 166 million patients have been tested positive worldwide with more than 3.4 million related death recorded. COVID-19 has a wide range of signs and symptoms. Hematological changes such as lymphopenia, thrombocytopenia, and coagulation disturbances are not unusual in patients with COVID-19. However, the mechanisms causing these changes are partially comprehended. Immune thrombocytopenia was identified to be among the hematologic autoimmune diseases seen in patients infected with SARS-CoV-2. This review summarizes the evidence on COVID-19-associated immune thrombocytopenia and the underlying mechanisms involved in its development.
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spelling doaj.art-f29dee1b6daa47eea30b1905d4e44d9d2022-12-22T00:37:06ZengAmaltea Medical Publishing HouseRomanian Journal of Infectious Diseases1454-33892069-60512021-06-01242637010.37897/RJID.2021.2.1COVID-19-associated immune thrombocytopeniaMara-Andrada Plesu0Gabriel Cristian Bejan1Ioana Veronica Grajdeanu2Anca Angela Simionescu3Ana Maria Alexandra Stanescu4Private Medical Practice Dr. Ioana Veronica Grajdeanu, Bucharest, RomaniaDepartment of Family Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Family Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Filantropia Clinical Hospital, Bucharest, RomaniaDepartment of Family Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaThe coronavirus disease 2019 (COVID-19) is a contagious respiratory tract infection caused by the betacoronavirus SARS-CoV-2. The World Health Organization declared the COVID-19 outbreak a pandemic on March 11, 2020. Since the COVID-19 pandemic started, more than 166 million patients have been tested positive worldwide with more than 3.4 million related death recorded. COVID-19 has a wide range of signs and symptoms. Hematological changes such as lymphopenia, thrombocytopenia, and coagulation disturbances are not unusual in patients with COVID-19. However, the mechanisms causing these changes are partially comprehended. Immune thrombocytopenia was identified to be among the hematologic autoimmune diseases seen in patients infected with SARS-CoV-2. This review summarizes the evidence on COVID-19-associated immune thrombocytopenia and the underlying mechanisms involved in its development.https://rjid.com.ro/articles/2021.2/RJID_2021_2_Art-01.pdfthrombocytopeniaimmune thrombocytopenic purpuracovid-19sars-cov-2coronavirus
spellingShingle Mara-Andrada Plesu
Gabriel Cristian Bejan
Ioana Veronica Grajdeanu
Anca Angela Simionescu
Ana Maria Alexandra Stanescu
COVID-19-associated immune thrombocytopenia
Romanian Journal of Infectious Diseases
thrombocytopenia
immune thrombocytopenic purpura
covid-19
sars-cov-2
coronavirus
title COVID-19-associated immune thrombocytopenia
title_full COVID-19-associated immune thrombocytopenia
title_fullStr COVID-19-associated immune thrombocytopenia
title_full_unstemmed COVID-19-associated immune thrombocytopenia
title_short COVID-19-associated immune thrombocytopenia
title_sort covid 19 associated immune thrombocytopenia
topic thrombocytopenia
immune thrombocytopenic purpura
covid-19
sars-cov-2
coronavirus
url https://rjid.com.ro/articles/2021.2/RJID_2021_2_Art-01.pdf
work_keys_str_mv AT maraandradaplesu covid19associatedimmunethrombocytopenia
AT gabrielcristianbejan covid19associatedimmunethrombocytopenia
AT ioanaveronicagrajdeanu covid19associatedimmunethrombocytopenia
AT ancaangelasimionescu covid19associatedimmunethrombocytopenia
AT anamariaalexandrastanescu covid19associatedimmunethrombocytopenia