Comprehensive overview of different medicinal parts from Morus alba L.: chemical compositions and pharmacological activities

Morus alba L., a common traditional Chinese medicine (TCM) with a centuries-old medicinal history, owned various medicinal parts like Mori folium, Mori ramulus, Mori cortex and Mori fructus. Different medical parts exhibit distinct modern pharmacological effects. Mori folium exhibited analgesic, ant...

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Main Authors: Yumei Wang, Qing Ai, Meiling Gu, Hong Guan, Wenqin Yang, Meng Zhang, Jialin Mao, Zhao Lin, Qi Liu, Jicheng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1364948/full
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author Yumei Wang
Qing Ai
Qing Ai
Meiling Gu
Meiling Gu
Hong Guan
Wenqin Yang
Meng Zhang
Meng Zhang
Jialin Mao
Zhao Lin
Qi Liu
Jicheng Liu
author_facet Yumei Wang
Qing Ai
Qing Ai
Meiling Gu
Meiling Gu
Hong Guan
Wenqin Yang
Meng Zhang
Meng Zhang
Jialin Mao
Zhao Lin
Qi Liu
Jicheng Liu
author_sort Yumei Wang
collection DOAJ
description Morus alba L., a common traditional Chinese medicine (TCM) with a centuries-old medicinal history, owned various medicinal parts like Mori folium, Mori ramulus, Mori cortex and Mori fructus. Different medical parts exhibit distinct modern pharmacological effects. Mori folium exhibited analgesic, anti-inflammatory, hypoglycemic action and lipid-regulation effects. Mori ramulus owned anti-bacterial, anti-asthmatic and diuretic activities. Mori cortex showed counteraction action of pain, inflammatory, bacterial, and platelet aggregation. Mori fructus could decompose fat, lower blood lipids and prevent vascular sclerosis. The main chemical components in Morus alba L. covered flavonoids, phenolic compounds, alkaloids, and amino acids. This article comprehensively analyzed the recent literature related to chemical components and pharmacological actions of M. alba L., summarizing 198 of ingredients and described the modern activities of different extracts and the bioactive constituents in the four parts from M. alba L. These results fully demonstrated the medicinal value of M. alba L., provided valuable references for further comprehensive development, and layed the foundation for the utilization of M. alba L.
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spelling doaj.art-f2a154b3b34f493eb4a81339ee858bc82024-04-17T04:34:35ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122024-04-011510.3389/fphar.2024.13649481364948Comprehensive overview of different medicinal parts from Morus alba L.: chemical compositions and pharmacological activitiesYumei Wang0Qing Ai1Qing Ai2Meiling Gu3Meiling Gu4Hong Guan5Wenqin Yang6Meng Zhang7Meng Zhang8Jialin Mao9Zhao Lin10Qi Liu11Jicheng Liu12The Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, ChinaThe Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, ChinaSchool of Pharmacy, Qiqihar Medical University, Qiqihar, ChinaThe Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, ChinaSchool of Pharmacy, Qiqihar Medical University, Qiqihar, ChinaOffice of Academic Research, Qiqihar Medical University, Qiqihar, ChinaOffice of Academic Research, Qiqihar Medical University, Qiqihar, ChinaThe Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, ChinaSchool of Pharmacy, Qiqihar Medical University, Qiqihar, ChinaThe Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, ChinaThe Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, ChinaThe Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, ChinaThe Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, ChinaMorus alba L., a common traditional Chinese medicine (TCM) with a centuries-old medicinal history, owned various medicinal parts like Mori folium, Mori ramulus, Mori cortex and Mori fructus. Different medical parts exhibit distinct modern pharmacological effects. Mori folium exhibited analgesic, anti-inflammatory, hypoglycemic action and lipid-regulation effects. Mori ramulus owned anti-bacterial, anti-asthmatic and diuretic activities. Mori cortex showed counteraction action of pain, inflammatory, bacterial, and platelet aggregation. Mori fructus could decompose fat, lower blood lipids and prevent vascular sclerosis. The main chemical components in Morus alba L. covered flavonoids, phenolic compounds, alkaloids, and amino acids. This article comprehensively analyzed the recent literature related to chemical components and pharmacological actions of M. alba L., summarizing 198 of ingredients and described the modern activities of different extracts and the bioactive constituents in the four parts from M. alba L. These results fully demonstrated the medicinal value of M. alba L., provided valuable references for further comprehensive development, and layed the foundation for the utilization of M. alba L.https://www.frontiersin.org/articles/10.3389/fphar.2024.1364948/fullMori foliumMori ramulusMori cortexMori fructuschemical constituentspharmacological activities
spellingShingle Yumei Wang
Qing Ai
Qing Ai
Meiling Gu
Meiling Gu
Hong Guan
Wenqin Yang
Meng Zhang
Meng Zhang
Jialin Mao
Zhao Lin
Qi Liu
Jicheng Liu
Comprehensive overview of different medicinal parts from Morus alba L.: chemical compositions and pharmacological activities
Frontiers in Pharmacology
Mori folium
Mori ramulus
Mori cortex
Mori fructus
chemical constituents
pharmacological activities
title Comprehensive overview of different medicinal parts from Morus alba L.: chemical compositions and pharmacological activities
title_full Comprehensive overview of different medicinal parts from Morus alba L.: chemical compositions and pharmacological activities
title_fullStr Comprehensive overview of different medicinal parts from Morus alba L.: chemical compositions and pharmacological activities
title_full_unstemmed Comprehensive overview of different medicinal parts from Morus alba L.: chemical compositions and pharmacological activities
title_short Comprehensive overview of different medicinal parts from Morus alba L.: chemical compositions and pharmacological activities
title_sort comprehensive overview of different medicinal parts from morus alba l chemical compositions and pharmacological activities
topic Mori folium
Mori ramulus
Mori cortex
Mori fructus
chemical constituents
pharmacological activities
url https://www.frontiersin.org/articles/10.3389/fphar.2024.1364948/full
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