Interrelationship between surging reproductive hormones and blood viscosity indices in apparently healthy females

Background: In active female reproductive life, a cascade of physiological phenomena occurs during each menstrual cycle day. Aim and Objectives: The study was designed to determine the relationship between surging reproductive hormones and blood viscosity indices. Material and Methods: One hundred...

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Bibliographic Details
Main Authors: Okeke Onyinye Cynthia, Ekakitie Ofovwe Obruche, Adeniyi Mayowa Jeremiah, Oyeyemi Adekunle Wahab, Ajayi Olutayo Ifedayo
Format: Article
Language:English
Published: Krishna Institute of Medical Sciences University 2023-04-01
Series:Journal of Krishna Institute of Medical Sciences University
Subjects:
Online Access:https://www.jkimsu.com/jkimsu-vol12no2/JKIMSU,%20Vol.%2012,%20No.%202,%20April-June%202023%20Page%2057-64.pdf
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Summary:Background: In active female reproductive life, a cascade of physiological phenomena occurs during each menstrual cycle day. Aim and Objectives: The study was designed to determine the relationship between surging reproductive hormones and blood viscosity indices. Material and Methods: One hundred apparently healthy females between the ages of 18-25 years, with regular cycle length of 28 days were recruited for the study. Reproductive hormones [Luteinizing Hormone (LH) and progesterone], blood viscosity indices [Relative Plasma Viscosity (RPV), fibrinogen and hematocrit] and other blood related parameters were analyzed during days 12, 13, 14 and 21 of menstrual cycle. Results: Progesterone secretion reached nadir and zenith on days 12 and 21 respectively while peak LH level occurred on day 12. On days 12 and 21, RPV correlated with progesterone negatively while on days 12 and 13, fibrinogen was inversely related to progesterone. Hematocrit correlated positively with progesterone throughout the menstrual cycle days. Although fibrinogen and mean corpuscular volume were unchanged throughout the menstrual cycle days, RPV was high on day 13. Significant decreases in red and white blood cell counts and hematocrit were observed on day 21. Conclusion: The findings of the study indicated that blood viscosity indices were not influenced by surges in progesterone and luteinizing hormone.
ISSN:2231-4261