Red shell‐ high risk normal tissue in stereotactic radiosurgery

Abstract Due to the ablative nature of high prescription in Stereotactic Radiosurgery or stereotactic body radiation therapy (SRS/SBRT), the normal tissue surrounding the CTV receives the dose higher than tissue's dose constraint. A concept of Red Shell is proposed to define and quantify these...

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Bibliographic Details
Main Authors: Jun Yang, Weihua Qi, Lei Wang, Qiuxia Lu, Liangfu Han, Brian Wang, Weisi Yan
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Precision Radiation Oncology
Subjects:
Online Access:https://doi.org/10.1002/pro6.1218
Description
Summary:Abstract Due to the ablative nature of high prescription in Stereotactic Radiosurgery or stereotactic body radiation therapy (SRS/SBRT), the normal tissue surrounding the CTV receives the dose higher than tissue's dose constraint. A concept of Red Shell is proposed to define and quantify these tissue damaged in SBRT, using biological equivalent dose (BED) concept. The combination of biological factors and physics factors, including serial and parallel organ, dose gradient, dose distribution and fractionations, are further discussed to interpret the clinical meaning of Red Shell. This concept can also help planner to improve the optimization in planning process.
ISSN:2398-7324