Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-01679-x |
| _version_ | 1828903195583184896 |
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| author | Hiroki Ikeda Masamitsu Sone Shinya Yamanaka Takuya Yamamoto |
| author_facet | Hiroki Ikeda Masamitsu Sone Shinya Yamanaka Takuya Yamamoto |
| author_sort | Hiroki Ikeda |
| collection | DOAJ |
| description | Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells. |
| first_indexed | 2024-12-13T16:29:16Z |
| format | Article |
| id | doaj.art-f2abb74fe82443a5a79daa922416e7d6 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-13T16:29:16Z |
| publishDate | 2017-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-f2abb74fe82443a5a79daa922416e7d62022-12-21T23:38:32ZengNature PortfolioNature Communications2041-17232017-11-018111310.1038/s41467-017-01679-xStructural and spatial chromatin features at developmental gene loci in human pluripotent stem cellsHiroki Ikeda0Masamitsu Sone1Shinya Yamanaka2Takuya Yamamoto3Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto UniversityDepartment of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto UniversityDepartment of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto UniversityDepartment of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto UniversityHigher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.https://doi.org/10.1038/s41467-017-01679-x |
| spellingShingle | Hiroki Ikeda Masamitsu Sone Shinya Yamanaka Takuya Yamamoto Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells Nature Communications |
| title | Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
| title_full | Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
| title_fullStr | Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
| title_full_unstemmed | Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
| title_short | Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
| title_sort | structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
| url | https://doi.org/10.1038/s41467-017-01679-x |
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