Ecological Adaptations of Gut Microbiota Members and Their Consequences for Use as a New Generation of Probiotics
In this review, we link ecological adaptations of different gut microbiota members with their potential for use as a new generation of probiotics. Gut microbiota members differ in their adaptations to survival in aerobic environments. Interestingly, there is an inverse relationship between aerobic s...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/11/5471 |
| _version_ | 1797533105753423872 |
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| author | Tereza Kubasova Zuzana Seidlerova Ivan Rychlik |
| author_facet | Tereza Kubasova Zuzana Seidlerova Ivan Rychlik |
| author_sort | Tereza Kubasova |
| collection | DOAJ |
| description | In this review, we link ecological adaptations of different gut microbiota members with their potential for use as a new generation of probiotics. Gut microbiota members differ in their adaptations to survival in aerobic environments. Interestingly, there is an inverse relationship between aerobic survival and abundance or potential for prolonged colonization of the intestinal tract. Facultative anaerobes, aerotolerant <i>Lactobacilli</i> and endospore-forming Firmicutes exhibit high fluctuation, and if such bacteria are to be used as probiotics, they must be continuously administered to mimic their permanent supply from the environment. On the other hand, species not expressing any form of aerobic resistance, such as those from phylum Bacteroidetes, commonly represent host-adapted microbiota members characterized by vertical transmission from mothers to offspring, capable of long-term colonization following a single dose administration. To achieve maximal probiotic efficacy, the mode of their administration should thus reflect their natural ecology. |
| first_indexed | 2024-03-10T11:09:51Z |
| format | Article |
| id | doaj.art-f2ad3c3157544bcbbc688f3b5ac2b57f |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T11:09:51Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-f2ad3c3157544bcbbc688f3b5ac2b57f2023-11-21T20:55:28ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-05-012211547110.3390/ijms22115471Ecological Adaptations of Gut Microbiota Members and Their Consequences for Use as a New Generation of ProbioticsTereza Kubasova0Zuzana Seidlerova1Ivan Rychlik2Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech RepublicVeterinary Research Institute, Hudcova 70, 621 00 Brno, Czech RepublicVeterinary Research Institute, Hudcova 70, 621 00 Brno, Czech RepublicIn this review, we link ecological adaptations of different gut microbiota members with their potential for use as a new generation of probiotics. Gut microbiota members differ in their adaptations to survival in aerobic environments. Interestingly, there is an inverse relationship between aerobic survival and abundance or potential for prolonged colonization of the intestinal tract. Facultative anaerobes, aerotolerant <i>Lactobacilli</i> and endospore-forming Firmicutes exhibit high fluctuation, and if such bacteria are to be used as probiotics, they must be continuously administered to mimic their permanent supply from the environment. On the other hand, species not expressing any form of aerobic resistance, such as those from phylum Bacteroidetes, commonly represent host-adapted microbiota members characterized by vertical transmission from mothers to offspring, capable of long-term colonization following a single dose administration. To achieve maximal probiotic efficacy, the mode of their administration should thus reflect their natural ecology.https://www.mdpi.com/1422-0067/22/11/5471gutmicrobiotachickenhumanpigprobiotics |
| spellingShingle | Tereza Kubasova Zuzana Seidlerova Ivan Rychlik Ecological Adaptations of Gut Microbiota Members and Their Consequences for Use as a New Generation of Probiotics International Journal of Molecular Sciences gut microbiota chicken human pig probiotics |
| title | Ecological Adaptations of Gut Microbiota Members and Their Consequences for Use as a New Generation of Probiotics |
| title_full | Ecological Adaptations of Gut Microbiota Members and Their Consequences for Use as a New Generation of Probiotics |
| title_fullStr | Ecological Adaptations of Gut Microbiota Members and Their Consequences for Use as a New Generation of Probiotics |
| title_full_unstemmed | Ecological Adaptations of Gut Microbiota Members and Their Consequences for Use as a New Generation of Probiotics |
| title_short | Ecological Adaptations of Gut Microbiota Members and Their Consequences for Use as a New Generation of Probiotics |
| title_sort | ecological adaptations of gut microbiota members and their consequences for use as a new generation of probiotics |
| topic | gut microbiota chicken human pig probiotics |
| url | https://www.mdpi.com/1422-0067/22/11/5471 |
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