Exploring links between vitamin D deficiency and COVID-19.
Coronavirus Disease 2019 (COVID-19) pandemic remains a major public health threat in most countries. The causative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can lead to acute respiratory distress syndrome and result in mortality in COVID-19 patients. Vitamin D is an immunomo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2020-09-01
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| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1008874 |
| _version_ | 1811305057491091456 |
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| author | Mradul Mohan Jerin Jose Cherian Amit Sharma |
| author_facet | Mradul Mohan Jerin Jose Cherian Amit Sharma |
| author_sort | Mradul Mohan |
| collection | DOAJ |
| description | Coronavirus Disease 2019 (COVID-19) pandemic remains a major public health threat in most countries. The causative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can lead to acute respiratory distress syndrome and result in mortality in COVID-19 patients. Vitamin D is an immunomodulator hormone with established effectiveness against various upper respiratory infections. Vitamin D can stall hyper-inflammatory responses and expedite healing process of the affected areas, primarily in the lung tissue. Thus, there are ecological and mechanistic reasons to promote exploration of vitamin D action in COVID-19 patients. As no curative drugs are available currently for COVID-19, we feel that the potential of vitamin D to alter the course of disease severity needs to be investigated. Clinical studies may be undertaken to address the value of vitamin D supplementation in deficient, high-risk COVID-19 patients. |
| first_indexed | 2024-04-13T08:18:33Z |
| format | Article |
| id | doaj.art-f2ae0c0ecf604751907aed881a97688d |
| institution | Directory Open Access Journal |
| issn | 1553-7366 1553-7374 |
| language | English |
| last_indexed | 2024-04-13T08:18:33Z |
| publishDate | 2020-09-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Pathogens |
| spelling | doaj.art-f2ae0c0ecf604751907aed881a97688d2022-12-22T02:54:42ZengPublic Library of Science (PLoS)PLoS Pathogens1553-73661553-73742020-09-01169e100887410.1371/journal.ppat.1008874Exploring links between vitamin D deficiency and COVID-19.Mradul MohanJerin Jose CherianAmit SharmaCoronavirus Disease 2019 (COVID-19) pandemic remains a major public health threat in most countries. The causative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can lead to acute respiratory distress syndrome and result in mortality in COVID-19 patients. Vitamin D is an immunomodulator hormone with established effectiveness against various upper respiratory infections. Vitamin D can stall hyper-inflammatory responses and expedite healing process of the affected areas, primarily in the lung tissue. Thus, there are ecological and mechanistic reasons to promote exploration of vitamin D action in COVID-19 patients. As no curative drugs are available currently for COVID-19, we feel that the potential of vitamin D to alter the course of disease severity needs to be investigated. Clinical studies may be undertaken to address the value of vitamin D supplementation in deficient, high-risk COVID-19 patients.https://doi.org/10.1371/journal.ppat.1008874 |
| spellingShingle | Mradul Mohan Jerin Jose Cherian Amit Sharma Exploring links between vitamin D deficiency and COVID-19. PLoS Pathogens |
| title | Exploring links between vitamin D deficiency and COVID-19. |
| title_full | Exploring links between vitamin D deficiency and COVID-19. |
| title_fullStr | Exploring links between vitamin D deficiency and COVID-19. |
| title_full_unstemmed | Exploring links between vitamin D deficiency and COVID-19. |
| title_short | Exploring links between vitamin D deficiency and COVID-19. |
| title_sort | exploring links between vitamin d deficiency and covid 19 |
| url | https://doi.org/10.1371/journal.ppat.1008874 |
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