Transcriptomic analysis reveals partial epithelial–mesenchymal transition and inflammation as common pathogenic mechanisms in hypertensive nephrosclerosis and Type 2 diabetic nephropathy
Abstract Hypertensive nephrosclerosis (HN) and Type 2 diabetic nephropathy (T2DN) are the leading causes of chronic kidney disease (CKD). To explore shared pathogenetic mechanisms, we analyzed transcriptomes of kidney biopsies from patients with HN or T2DN. Total RNA was extracted from 10 μm whole k...
Main Authors: | Ole Petter Nordbø, Lea Landolt, Øystein Eikrem, Andreas Scherer, Sabine Leh, Jessica Furriol, Terje Apeland, Piotr Mydel, Hans‐Peter Marti |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-10-01
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Series: | Physiological Reports |
Subjects: | |
Online Access: | https://doi.org/10.14814/phy2.15825 |
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