How well do we need to control blood glucose before discharging DKA patients? A retrospective cohort study

Purpose: To determine the ideal length of stay and glycemic control after resolution of acidosis in patients hospitalized for diabetic ketoacidosis, in order to reduce 30-day readmission. We hypothesized that both discharging patients within 24 hours of acidosis resolution and hyperglycemia at disch...

Full description

Bibliographic Details
Main Authors: Chi Tang, Ruth Kouides
Format: Article
Language:English
Published: Greater Baltimore Medical Center 2014-11-01
Series:Journal of Community Hospital Internal Medicine Perspectives
Subjects:
Online Access:http://www.jchimp.net/index.php/jchimp/article/download/25755/pdf_1
_version_ 1797969792373620736
author Chi Tang
Ruth Kouides
author_facet Chi Tang
Ruth Kouides
author_sort Chi Tang
collection DOAJ
description Purpose: To determine the ideal length of stay and glycemic control after resolution of acidosis in patients hospitalized for diabetic ketoacidosis, in order to reduce 30-day readmission. We hypothesized that both discharging patients within 24 hours of acidosis resolution and hyperglycemia at discharge are associated with higher probability of readmission. Methods: We examined data from 208 consecutive patients hospitalized for diabetic ketoacidosis. Logistic regression was performed adjusting for age, blood glucose (BG) level at presentation, prior hospitalization within 30 days, season of current hospitalization, and length of hospital stay. Results: Higher BG at discharge is associated with lower probability of readmission (odds ratio, 0.990; 95% CI, 0.983–0.996; P=0.002). Higher average BG over the 24 hours prior to discharge is also associated with lower readmission rate (odds ratio, 0.991; 95% CI, 0.982–1.000; P=0.044). The direction of the association remains the same even after these predictive variables are converted to categorical variables. In addition, discharge within 24 hours of acidosis resolution is not inferior to discharge after 24 hours of normalized BG (odds ratio, 0.431; 95% CI, 0.083–2.252; P=0.318). Conclusion: Neither discharging patients within 24 hours of acidosis resolution nor hyperglycemia at discharge is associated with higher readmission rate. Randomized prospective studies are needed to confirm or refute our study.
first_indexed 2024-04-11T03:07:48Z
format Article
id doaj.art-f2b1849e335c4a468abb8b90e7cc4c9d
institution Directory Open Access Journal
issn 2000-9666
language English
last_indexed 2024-04-11T03:07:48Z
publishDate 2014-11-01
publisher Greater Baltimore Medical Center
record_format Article
series Journal of Community Hospital Internal Medicine Perspectives
spelling doaj.art-f2b1849e335c4a468abb8b90e7cc4c9d2023-01-02T12:50:16ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662014-11-01451510.3402/jchimp.v4.2575525755How well do we need to control blood glucose before discharging DKA patients? A retrospective cohort studyChi Tang0Ruth Kouides1Department of Medicine, Unity Health System, Rochester, New York, USADepartment of Medicine, Unity Health System, Rochester, New York, USAPurpose: To determine the ideal length of stay and glycemic control after resolution of acidosis in patients hospitalized for diabetic ketoacidosis, in order to reduce 30-day readmission. We hypothesized that both discharging patients within 24 hours of acidosis resolution and hyperglycemia at discharge are associated with higher probability of readmission. Methods: We examined data from 208 consecutive patients hospitalized for diabetic ketoacidosis. Logistic regression was performed adjusting for age, blood glucose (BG) level at presentation, prior hospitalization within 30 days, season of current hospitalization, and length of hospital stay. Results: Higher BG at discharge is associated with lower probability of readmission (odds ratio, 0.990; 95% CI, 0.983–0.996; P=0.002). Higher average BG over the 24 hours prior to discharge is also associated with lower readmission rate (odds ratio, 0.991; 95% CI, 0.982–1.000; P=0.044). The direction of the association remains the same even after these predictive variables are converted to categorical variables. In addition, discharge within 24 hours of acidosis resolution is not inferior to discharge after 24 hours of normalized BG (odds ratio, 0.431; 95% CI, 0.083–2.252; P=0.318). Conclusion: Neither discharging patients within 24 hours of acidosis resolution nor hyperglycemia at discharge is associated with higher readmission rate. Randomized prospective studies are needed to confirm or refute our study.http://www.jchimp.net/index.php/jchimp/article/download/25755/pdf_1diabetic ketoacidosisreadmissionrisk factorshospitalizationhyperglycemialength of stay
spellingShingle Chi Tang
Ruth Kouides
How well do we need to control blood glucose before discharging DKA patients? A retrospective cohort study
Journal of Community Hospital Internal Medicine Perspectives
diabetic ketoacidosis
readmission
risk factors
hospitalization
hyperglycemia
length of stay
title How well do we need to control blood glucose before discharging DKA patients? A retrospective cohort study
title_full How well do we need to control blood glucose before discharging DKA patients? A retrospective cohort study
title_fullStr How well do we need to control blood glucose before discharging DKA patients? A retrospective cohort study
title_full_unstemmed How well do we need to control blood glucose before discharging DKA patients? A retrospective cohort study
title_short How well do we need to control blood glucose before discharging DKA patients? A retrospective cohort study
title_sort how well do we need to control blood glucose before discharging dka patients a retrospective cohort study
topic diabetic ketoacidosis
readmission
risk factors
hospitalization
hyperglycemia
length of stay
url http://www.jchimp.net/index.php/jchimp/article/download/25755/pdf_1
work_keys_str_mv AT chitang howwelldoweneedtocontrolbloodglucosebeforedischargingdkapatientsaretrospectivecohortstudy
AT ruthkouides howwelldoweneedtocontrolbloodglucosebeforedischargingdkapatientsaretrospectivecohortstudy