Synthesis, Antifungal Activity, and 3D-QSAR Study of Novel Nopol-Derived 1,3,4-Thiadiazole-Thiourea Compounds

Synthesis, Antifungal Activity, and 3D-QSAR Study of Novel Nopol-Derived 1,3,4-Thiadiazole-Thiourea Compounds

A series of novel nopol derivatives bearing the 1,3,4-thiadiazole-thiourea moiety were designed and synthesized by multi-step reactions in search of potent natural product-based antifungal agents. Their structures were confirmed by FT-IR, NMR, ESI-MS, and elemental analysis. Antifungal activity of t...

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Bibliographic Details
Main Authors:	Ming Chen, Wen-Gui Duan, Gui-Shan Lin, Zhong-Tian Fan, Xiu Wang
Format:	Article
Language:	English
Published:	MDPI AG 2021-03-01
Series:	Molecules
Subjects:	<i>β</i>-pinene nopol 1,3,4-thiadiazole thiourea antifungal activity 3D-QSAR
Online Access:	https://www.mdpi.com/1420-3049/26/6/1708

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