LcSAO1, an Unconventional DOXB Clade 2OGD Enzyme from <i>Ligusticum chuanxiong</i> Catalyzes the Biosynthesis of Plant-Derived Natural Medicine Butylphthalide

LcSAO1, an Unconventional DOXB Clade 2OGD Enzyme from <i>Ligusticum chuanxiong</i> Catalyzes the Biosynthesis of Plant-Derived Natural Medicine Butylphthalide

Butylphthalide, a prescription medicine recognized for its efficacy in treating ischemic strokes approved by the State Food and Drug Administration of China in 2005, is sourced from the traditional botanical remedy <i>Ligusticum chuanxiong</i>. While chemical synthesis offers a viable ro...

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Bibliographic Details
Main Authors: Xueqing Chen, Xiaopeng Zhang, Wenkai Sun, Zhuangwei Hou, Bao Nie, Fengjiao Wang, Song Yang, Shourui Feng, Wei Li, Li Wang
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
butylphthalide
desaturation
Fe (II)/2-oxoglutarate-dependent dioxygenase
<i>Ligusticum chuanxiong</i>
Online Access:https://www.mdpi.com/1422-0067/24/24/17417

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