Paliurus spina-christi Mill fruit extracts improve glucose uptake and activate the insulin signaling pathways in HepG2 insulin-resistant cells

Paliurus spina-christi Mill fruit extracts improve glucose uptake and activate the insulin signaling pathways in HepG2 insulin-resistant cells

Abstract Background Paliurus spina-christi Mill. (PSC) fruit is frequently used in the treatment of diabetes mellitus in Mediterranean regions. Here, we investigated the effects of various PSC fruit extracts (PSC-FEs) on glucose consumption and some key mediators of insulin signaling pathways in hig...

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Bibliographic Details
Main Authors: Seyedeh Mona Mousavi Esfahani, Parastoo Tarighi, Kosar Dianat, Tabarek Mahdi Ashour, Negar Mottaghi-Dastjerdi, Mehdi Aghsami, Mahsa Sabernavaei, Hamed Montazeri
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Paliurus spina-christi Mill
Diabetes
AMP-activated protein kinase (AMPK)
AKT
GLUT1
GLUT4
Online Access:https://doi.org/10.1186/s12906-023-03977-y

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