Dexmedetomidine attenuates subarachnoid hemorrhage-induced acute lung injury through regulating autophagy and TLR/NFκB signaling pathway

Dexmedetomidine attenuates subarachnoid hemorrhage-induced acute lung injury through regulating autophagy and TLR/NFκB signaling pathway

Background Acute lung injury (ALI) is the most serious complication of subarachnoid hemorrhage (SAH). We investigated role of autophagy and inflammatory signaling pathways in lung damage and therapeutic effects of dexmedetomidine (DEX). Methods Fifty male Wistar rats were randomly divided into five...

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Bibliographic Details
Main Authors: Dong Woo Han, Ju Eun Oh, Beom Jin Lim, Yeonseung Han, Young Song
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2022-12-01
Series:Korean Journal of Anesthesiology
Subjects:
acute lung injury
autophagy
dexmedetomidine
inflammation
subarachnoid hemorrhage
toll-like receptors
Online Access:http://ekja.org/upload/pdf/kja-22165.pdf

Internet

http://ekja.org/upload/pdf/kja-22165.pdf

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