Pyrethroids exposure alters the community and function of the internal microbiota in Aedes albopictus
Large amounts of insecticides bring selection pressure and then develop insecticide resistance in Aedes albopictus. This study demonstrated for the first time the effect of pyrethroid exposure on the internal microbiota in Ae. albopictus. 36, 48, 57 strains of virgin adult Ae. albopictus were expose...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651323000830 |
| _version_ | 1797903068806774784 |
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| author | Xiao Wei Hong Peng Yan Li Biao Meng Shichao Wang Shanzheng Bi Xiangna Zhao |
| author_facet | Xiao Wei Hong Peng Yan Li Biao Meng Shichao Wang Shanzheng Bi Xiangna Zhao |
| author_sort | Xiao Wei |
| collection | DOAJ |
| description | Large amounts of insecticides bring selection pressure and then develop insecticide resistance in Aedes albopictus. This study demonstrated for the first time the effect of pyrethroid exposure on the internal microbiota in Ae. albopictus. 36, 48, 57 strains of virgin adult Ae. albopictus were exposed to the pyrethroids deltamethrin (Dme group), β-cypermethrin (Bcy group), and cis-permethrin (Cper group), respectively, with n-hexane exposure (Hex group) as the controls (n = 36). The internal microbiota community and functions were analyzed based on the metagenomic analysis. The analysis of similarity (ANOSIM) results showed that the Hex/Bcy (p = 0.001), Hex/Cper (p = 0.006), Hex/Dme (p = 0.001) groups were well separated, and the internal microbes of Ae. albopictus vary in the composition and functions depending on the type of pyrethroid insecticide they are applied. Four short chain fatty acid-producing genera, Butyricimonas, Prevotellaceae, Anaerococcus, Pseudorhodobacter were specifically absent in the pyrethroid-exposed mosquitoes. Morganella and Streptomyces were significantly enriched in cis-permethrin-exposed mosquitoes. Wolbachia and Chryseobacterium showed significant enrichment in β-cypermethrin-exposed mosquitoes. Pseudomonas was significantly abundant in deltamethrin-exposed mosquitoes. The significant proliferation of these bacteria may be closely related to insecticide metabolism. Our study recapitulated a specifically enhanced metabolic networks relevant to the exposure to cis-permethrin and β-cypermethrin, respectively. Benzaldehyde dehydrogenase (EC 1.2.1.28), key enzyme in aromatic compounds metabolism, was detected enhanced in cis-permethrin and β-cypermethrin exposed mosquitoes. The internal microbiota metabolism of aromatic compounds may be important influencing factors for pyrethroid resistance. Future work will be needed to elucidate the specific mechanisms by which mosquito microbiota influences host resistance and vector ability. |
| first_indexed | 2024-04-10T09:27:09Z |
| format | Article |
| id | doaj.art-f2b5e3b4d9f142dca2226c0062dabf87 |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-04-10T09:27:09Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-f2b5e3b4d9f142dca2226c0062dabf872023-02-20T04:08:33ZengElsevierEcotoxicology and Environmental Safety0147-65132023-03-01252114579Pyrethroids exposure alters the community and function of the internal microbiota in Aedes albopictusXiao Wei0Hong Peng1Yan Li2Biao Meng3Shichao Wang4Shanzheng Bi5Xiangna Zhao6Centers for Disease Control and Prevention of PLA, Beijing, ChinaCenters for Disease Control and Prevention of PLA, Beijing, ChinaCenters for Disease Control and Prevention of PLA, Beijing, ChinaCenters for Disease Control and Prevention of PLA, Beijing, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, ChinaCenters for Disease Control and Prevention of PLA, Beijing, ChinaCenters for Disease Control and Prevention of PLA, Beijing, ChinaCenters for Disease Control and Prevention of PLA, Beijing, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, China; Corresponding author at: Centers for Disease Control and Prevention of PLA, Beijing, China.Large amounts of insecticides bring selection pressure and then develop insecticide resistance in Aedes albopictus. This study demonstrated for the first time the effect of pyrethroid exposure on the internal microbiota in Ae. albopictus. 36, 48, 57 strains of virgin adult Ae. albopictus were exposed to the pyrethroids deltamethrin (Dme group), β-cypermethrin (Bcy group), and cis-permethrin (Cper group), respectively, with n-hexane exposure (Hex group) as the controls (n = 36). The internal microbiota community and functions were analyzed based on the metagenomic analysis. The analysis of similarity (ANOSIM) results showed that the Hex/Bcy (p = 0.001), Hex/Cper (p = 0.006), Hex/Dme (p = 0.001) groups were well separated, and the internal microbes of Ae. albopictus vary in the composition and functions depending on the type of pyrethroid insecticide they are applied. Four short chain fatty acid-producing genera, Butyricimonas, Prevotellaceae, Anaerococcus, Pseudorhodobacter were specifically absent in the pyrethroid-exposed mosquitoes. Morganella and Streptomyces were significantly enriched in cis-permethrin-exposed mosquitoes. Wolbachia and Chryseobacterium showed significant enrichment in β-cypermethrin-exposed mosquitoes. Pseudomonas was significantly abundant in deltamethrin-exposed mosquitoes. The significant proliferation of these bacteria may be closely related to insecticide metabolism. Our study recapitulated a specifically enhanced metabolic networks relevant to the exposure to cis-permethrin and β-cypermethrin, respectively. Benzaldehyde dehydrogenase (EC 1.2.1.28), key enzyme in aromatic compounds metabolism, was detected enhanced in cis-permethrin and β-cypermethrin exposed mosquitoes. The internal microbiota metabolism of aromatic compounds may be important influencing factors for pyrethroid resistance. Future work will be needed to elucidate the specific mechanisms by which mosquito microbiota influences host resistance and vector ability.http://www.sciencedirect.com/science/article/pii/S0147651323000830Aedes aegyptiInternal microbiotaPyrethroidAromatic compoundsBenzaldehyde dehydrogenase |
| spellingShingle | Xiao Wei Hong Peng Yan Li Biao Meng Shichao Wang Shanzheng Bi Xiangna Zhao Pyrethroids exposure alters the community and function of the internal microbiota in Aedes albopictus Ecotoxicology and Environmental Safety Aedes aegypti Internal microbiota Pyrethroid Aromatic compounds Benzaldehyde dehydrogenase |
| title | Pyrethroids exposure alters the community and function of the internal microbiota in Aedes albopictus |
| title_full | Pyrethroids exposure alters the community and function of the internal microbiota in Aedes albopictus |
| title_fullStr | Pyrethroids exposure alters the community and function of the internal microbiota in Aedes albopictus |
| title_full_unstemmed | Pyrethroids exposure alters the community and function of the internal microbiota in Aedes albopictus |
| title_short | Pyrethroids exposure alters the community and function of the internal microbiota in Aedes albopictus |
| title_sort | pyrethroids exposure alters the community and function of the internal microbiota in aedes albopictus |
| topic | Aedes aegypti Internal microbiota Pyrethroid Aromatic compounds Benzaldehyde dehydrogenase |
| url | http://www.sciencedirect.com/science/article/pii/S0147651323000830 |
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