Phytocannabinoid Compositions from Cannabis Act Synergistically with PARP1 Inhibitor against Ovarian Cancer Cells In Vitro and Affect the Wnt Signaling Pathway

Phytocannabinoid Compositions from Cannabis Act Synergistically with PARP1 Inhibitor against Ovarian Cancer Cells In Vitro and Affect the Wnt Signaling Pathway

Ovarian cancer (OC) is the single most lethal gynecologic malignancy. <i>Cannabis sativa</i> is used to treat various medical conditions, and is cytotoxic to a variety of cancer types. We sought to examine the effectiveness of different combinations of cannabis compounds against OC. Cyto...

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Bibliographic Details
Main Authors: Nurit Shalev, Michelle Kendall, Seegehalli M. Anil, Sudeep Tiwari, Hadar Peeri, Navin Kumar, Eduard Belausov, Ajjampura C. Vinayaka, Hinanit Koltai
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
ovarian cancer
cannabis
phytocannabinoids
apoptosis
cytotoxicity
Wnt pathway
Online Access:https://www.mdpi.com/1420-3049/27/21/7523

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