GPX8+ cancer-associated fibroblast, as a cancer-promoting factor in lung adenocarcinoma, is related to the immunosuppressive microenvironment

GPX8+ cancer-associated fibroblast, as a cancer-promoting factor in lung adenocarcinoma, is related to the immunosuppressive microenvironment

Abstract Background Cancer-associated fibroblasts (CAFs) play a crucial role in the tumor microenvironment of lung adenocarcinoma (LUAD) and are often associated with poorer clinical outcomes. This study aimed to screen for CAF-specific genes that could serve as promising therapeutic targets for LUA...

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Bibliographic Details
Main Authors: Ying Bai, Tao Han, Yunjia Dong, Chao Liang, Lu Gao, Yafeng Liu, Jiawei Zhou, Jianqiang Guo, Deyong Ge, Jing Wu, Dong Hu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Medical Genomics
Subjects:
Lung adenocarcinoma
GPX8
Cancer-associated fibroblasts
Prognosis
Immunosuppressive microenvironment
Online Access:https://doi.org/10.1186/s12920-024-01832-8

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