Early identification of NORSE and transfer to care setting with appropriate supports: A proposed algorithm
New-onset refractory status epilepticus (NORSE) is a clinical presentation where an individual develops refractory status epilepticus without active epilepsy, or related neurological conditions. A subset of these individuals has a preceding fever and would be diagnosed with febrile infection-related...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1072020/full |
| _version_ | 1797849209490112512 |
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| author | Sarah A. Vinette Gordon Bryan Young Houman Khosravani |
| author_facet | Sarah A. Vinette Gordon Bryan Young Houman Khosravani |
| author_sort | Sarah A. Vinette |
| collection | DOAJ |
| description | New-onset refractory status epilepticus (NORSE) is a clinical presentation where an individual develops refractory status epilepticus without active epilepsy, or related neurological conditions. A subset of these individuals has a preceding fever and would be diagnosed with febrile infection-related epilepsy syndrome (FIRES). The underlying etiology of this condition varies and includes autoimmune and viral encephalitides. These conditions require multiple specialized health care teams working collaboratively and specific resources for investigation of the underlying etiology and management to provide optimal patient care. In this paper, we provide: (1) recommendations upon early recognition of NORSE and FIRES, (2) guidance on the resources needed to optimally provide care, and (3) guidance on considerations to initiate transfer of patients to a more specialized medical center. Additional recommendations for resource-austere centers without the ability to transfer such patients are also discussed. These recommendations are only for adult patients with NORSE as pediatric patients may require additional special considerations. |
| first_indexed | 2024-04-09T18:41:16Z |
| format | Article |
| id | doaj.art-f2b797e530cf4b2b881542347bad89d0 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-09T18:41:16Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-f2b797e530cf4b2b881542347bad89d02023-04-11T05:40:14ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-04-011410.3389/fneur.2023.10720201072020Early identification of NORSE and transfer to care setting with appropriate supports: A proposed algorithmSarah A. Vinette0Gordon Bryan Young1Houman Khosravani2Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, CanadaGrey Bruce Health Services, Owen Sound, ON, CanadaHurvitz Brain Sciences Program, Neurology Quality and Innovation Lab, Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, CanadaNew-onset refractory status epilepticus (NORSE) is a clinical presentation where an individual develops refractory status epilepticus without active epilepsy, or related neurological conditions. A subset of these individuals has a preceding fever and would be diagnosed with febrile infection-related epilepsy syndrome (FIRES). The underlying etiology of this condition varies and includes autoimmune and viral encephalitides. These conditions require multiple specialized health care teams working collaboratively and specific resources for investigation of the underlying etiology and management to provide optimal patient care. In this paper, we provide: (1) recommendations upon early recognition of NORSE and FIRES, (2) guidance on the resources needed to optimally provide care, and (3) guidance on considerations to initiate transfer of patients to a more specialized medical center. Additional recommendations for resource-austere centers without the ability to transfer such patients are also discussed. These recommendations are only for adult patients with NORSE as pediatric patients may require additional special considerations.https://www.frontiersin.org/articles/10.3389/fneur.2023.1072020/fullNORSEFIRESstatus epilepticusepilepsyneurocritical care |
| spellingShingle | Sarah A. Vinette Gordon Bryan Young Houman Khosravani Early identification of NORSE and transfer to care setting with appropriate supports: A proposed algorithm Frontiers in Neurology NORSE FIRES status epilepticus epilepsy neurocritical care |
| title | Early identification of NORSE and transfer to care setting with appropriate supports: A proposed algorithm |
| title_full | Early identification of NORSE and transfer to care setting with appropriate supports: A proposed algorithm |
| title_fullStr | Early identification of NORSE and transfer to care setting with appropriate supports: A proposed algorithm |
| title_full_unstemmed | Early identification of NORSE and transfer to care setting with appropriate supports: A proposed algorithm |
| title_short | Early identification of NORSE and transfer to care setting with appropriate supports: A proposed algorithm |
| title_sort | early identification of norse and transfer to care setting with appropriate supports a proposed algorithm |
| topic | NORSE FIRES status epilepticus epilepsy neurocritical care |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1072020/full |
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