CSF Biomarkers of Neurodegeneration in Progressive Non-fluent Aphasia and Other Forms of Frontotemporal Dementia: Clues for Pathomechanisms?

CSF Biomarkers of Neurodegeneration in Progressive Non-fluent Aphasia and Other Forms of Frontotemporal Dementia: Clues for Pathomechanisms?

Frontotemporal Dementia (FTD) encompasses distinct pathophysiologically heterogenous disorders with different genetic and cellular disease mechanisms. The objective of this study is to compare the constellation of biomarkers of neurodegeneration in the cerebrospinal fluid (CSF) to the FTD type categ...

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Bibliographic Details
Main Authors: Peter Körtvelyessy, Hans J. Heinze, Johannes Prudlo, Daniel Bittner
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Neurology
Subjects:
frontotemporal dementia
cerebrospinal fluid
phospho-tau
tau
amyloid beta
progranulin
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00504/full

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