Clinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodules
Abstract Background To evaluate the diagnostic value of American College of Radiology (ACR) score and ACR Thyroid Imaging Report and Data System (TI-RADS) for benign nodules, medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) through comparing with Kwak TI-RADS. Methods Five hun...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Endocrine Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12902-022-01053-z |
| _version_ | 1818209984512524288 |
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| author | Ziwei Zhang Ning Lin |
| author_facet | Ziwei Zhang Ning Lin |
| author_sort | Ziwei Zhang |
| collection | DOAJ |
| description | Abstract Background To evaluate the diagnostic value of American College of Radiology (ACR) score and ACR Thyroid Imaging Report and Data System (TI-RADS) for benign nodules, medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) through comparing with Kwak TI-RADS. Methods Five hundred nine patients diagnosed with PTC, MTC or benign thyroid nodules were included and classified into the benign thyroid nodules group (n = 264), the PTC group (n = 189) and the MTC group (n = 56). The area under the curve (AUC) values were analyzed and the receiver operator characteristic (ROC) curves were drawn to compare the diagnostic efficiencies of ACR score, ACR TI-RADS and KWAK TI-RADS on benign thyroid nodules, MTC and PTC. Results The AUC values of ACR score, ACR TI-RADS and Kwak TI-RADS for distinguishing malignant nodules from benign nodules were 0.914 (95%CI: 0.886–0.937), 0.871 (95%CI: 0.839–0.899) and 0.885 (95%CI: 0.854–0.911), respectively. In distinguishing of patients with MTC from PTC, the AUC values of ACR score, ACR TI-RADS and Kwak TI-RADS were 0.650 (95%CI: 0.565–0.734), 0.596 (95%CI: 0.527–0.664), and 0.613 (95%CI: 0.545–0.681), respectively. The AUC values of ACR score, ACR TI-RADS and Kwak TI-RADS for the discrimination of patients with MTC, PTC or benign nodules from patients without MTC, PTC or benign nodules were 0.899 (95%CI: 0.882–0.915), 0.865 (95%CI: 0.846–0.885), and 0.873 (95%CI: 0.854–0.893), respectively. Conclusion The ACR score performed the best, followed ex aequo by the ACR and Kwak TI-RADS in discriminating patients with malignant nodules from benign nodules and patients with MTC from PTC. |
| first_indexed | 2024-12-12T05:09:24Z |
| format | Article |
| id | doaj.art-f2c23b0a06f244cc8d763b6e6c8d2f5b |
| institution | Directory Open Access Journal |
| issn | 1472-6823 |
| language | English |
| last_indexed | 2024-12-12T05:09:24Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Endocrine Disorders |
| spelling | doaj.art-f2c23b0a06f244cc8d763b6e6c8d2f5b2022-12-22T00:37:00ZengBMCBMC Endocrine Disorders1472-68232022-05-0122111510.1186/s12902-022-01053-zClinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodulesZiwei Zhang0Ning Lin1Ultrasonography Department, Fujian Provincial HospitalUltrasonography Department, Fujian Provincial HospitalAbstract Background To evaluate the diagnostic value of American College of Radiology (ACR) score and ACR Thyroid Imaging Report and Data System (TI-RADS) for benign nodules, medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) through comparing with Kwak TI-RADS. Methods Five hundred nine patients diagnosed with PTC, MTC or benign thyroid nodules were included and classified into the benign thyroid nodules group (n = 264), the PTC group (n = 189) and the MTC group (n = 56). The area under the curve (AUC) values were analyzed and the receiver operator characteristic (ROC) curves were drawn to compare the diagnostic efficiencies of ACR score, ACR TI-RADS and KWAK TI-RADS on benign thyroid nodules, MTC and PTC. Results The AUC values of ACR score, ACR TI-RADS and Kwak TI-RADS for distinguishing malignant nodules from benign nodules were 0.914 (95%CI: 0.886–0.937), 0.871 (95%CI: 0.839–0.899) and 0.885 (95%CI: 0.854–0.911), respectively. In distinguishing of patients with MTC from PTC, the AUC values of ACR score, ACR TI-RADS and Kwak TI-RADS were 0.650 (95%CI: 0.565–0.734), 0.596 (95%CI: 0.527–0.664), and 0.613 (95%CI: 0.545–0.681), respectively. The AUC values of ACR score, ACR TI-RADS and Kwak TI-RADS for the discrimination of patients with MTC, PTC or benign nodules from patients without MTC, PTC or benign nodules were 0.899 (95%CI: 0.882–0.915), 0.865 (95%CI: 0.846–0.885), and 0.873 (95%CI: 0.854–0.893), respectively. Conclusion The ACR score performed the best, followed ex aequo by the ACR and Kwak TI-RADS in discriminating patients with malignant nodules from benign nodules and patients with MTC from PTC.https://doi.org/10.1186/s12902-022-01053-zDiagnostic valueMTCPTCACR scoreACR TI-RADS |
| spellingShingle | Ziwei Zhang Ning Lin Clinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodules BMC Endocrine Disorders Diagnostic value MTC PTC ACR score ACR TI-RADS |
| title | Clinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodules |
| title_full | Clinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodules |
| title_fullStr | Clinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodules |
| title_full_unstemmed | Clinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodules |
| title_short | Clinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodules |
| title_sort | clinical diagnostic value of american college of radiology thyroid imaging report and data system in different kinds of thyroid nodules |
| topic | Diagnostic value MTC PTC ACR score ACR TI-RADS |
| url | https://doi.org/10.1186/s12902-022-01053-z |
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