The evaluation of tumorigenicity and characterization of colonies in a soft agar colony formation assay using polymerase chain reaction

Abstract In regenerative medicine, the tumorigenic potency of cells in cellular therapy products (CTPs) is a major concern for their application to patients. This study presents a method—the soft agar colony formation assay using polymerase chain reaction (PCR)—to evaluate tumorigenicity. MRC-5 cell...

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Bibliographic Details
Main Author: Daichi Nakamura
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32442-6