A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles

A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles

Summary: N(6)-methyladenosine (m6A) critically regulates RNA dynamics in various biological processes. The m6A demethylase ALKBH5 promotes tumorigenesis of glioblastoma, while the intricate web that orchestrates its regulation remains enigmatic. Here, we discover that cell density affects ALKBH5 sub...

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Bibliographic Details
Main Authors: Lei Cao, Ruohui Han, Yingying Zhao, Xiaoyang Qin, Qian Li, Hui Xiong, Yu Kong, Ziyi Liu, Zexing Li, Feng Dong, Ting Li, Xiujuan Zhao, Lei Lei, Qian Zhao, Dayong Liu, Baofeng Wang, Xudong Wu
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724003607

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