Invasive Cystic Hypersecretory Carcinoma of Breast: A Rare and Under Diagnosed Variant of Ductal Carcinoma

Handful cases of invasive Cystic Hypersecretory Ductal Carcinoma (CHC) have been reported so far in literature. Cystic hypersecretory lesions of breast have a spectrum of morphological features ranging from Cystic Hypersecretory Hyperplasia (CHH), CHH with atypia, in situ to invasive CHC. We are r...

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Main Authors: Nibedita Sahoo, Pritinanda Mishra, Susama Patra, Prakash Kumar Sasmal
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/10098/27937_CE_F(RK)_PF1(PrGGH)_PFA(RU_PrG).pdf
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author Nibedita Sahoo
Pritinanda Mishra
Susama Patra
Prakash Kumar Sasmal
author_facet Nibedita Sahoo
Pritinanda Mishra
Susama Patra
Prakash Kumar Sasmal
author_sort Nibedita Sahoo
collection DOAJ
description Handful cases of invasive Cystic Hypersecretory Ductal Carcinoma (CHC) have been reported so far in literature. Cystic hypersecretory lesions of breast have a spectrum of morphological features ranging from Cystic Hypersecretory Hyperplasia (CHH), CHH with atypia, in situ to invasive CHC. We are reporting a case of a 32-year-old female who had nipple discharge and lump in her right breast for one month. A modified radical mastectomy was done and morphological diagnosis of invasive CHC with axillary node metastasis was made. The postoperative events were uneventful. Invasive CHC being a rare entity, our understanding of its biological behavior, prognostic factors and genetic basis is limited. The authors are aware of only 15 similar cases being reported in the English literature.
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spelling doaj.art-f2ca84659066460a90836d8ad58be9cc2022-12-21T17:49:40ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-06-01116ED16ED1710.7860/JCDR/2017/27937.10098Invasive Cystic Hypersecretory Carcinoma of Breast: A Rare and Under Diagnosed Variant of Ductal CarcinomaNibedita Sahoo0Pritinanda Mishra1Susama Patra2Prakash Kumar Sasmal3Senior Resident, Department of Pathology, AIIMS, Bhubaneswar, Odisha, India.Associate Professor, Department of Pathology, AIIMS, Bhubaneswar, Odisha, India.Professor, Department of Pathology, AIIMS, Bhubaneswar, Odisha, India.Assistant Professor, Department of Surgery, AIIMS, Bhubaneswar, Odisha, India.Handful cases of invasive Cystic Hypersecretory Ductal Carcinoma (CHC) have been reported so far in literature. Cystic hypersecretory lesions of breast have a spectrum of morphological features ranging from Cystic Hypersecretory Hyperplasia (CHH), CHH with atypia, in situ to invasive CHC. We are reporting a case of a 32-year-old female who had nipple discharge and lump in her right breast for one month. A modified radical mastectomy was done and morphological diagnosis of invasive CHC with axillary node metastasis was made. The postoperative events were uneventful. Invasive CHC being a rare entity, our understanding of its biological behavior, prognostic factors and genetic basis is limited. The authors are aware of only 15 similar cases being reported in the English literature.https://jcdr.net/articles/PDF/10098/27937_CE_F(RK)_PF1(PrGGH)_PFA(RU_PrG).pdfbreast carcinomadischargelumpmastectomy
spellingShingle Nibedita Sahoo
Pritinanda Mishra
Susama Patra
Prakash Kumar Sasmal
Invasive Cystic Hypersecretory Carcinoma of Breast: A Rare and Under Diagnosed Variant of Ductal Carcinoma
Journal of Clinical and Diagnostic Research
breast carcinoma
discharge
lump
mastectomy
title Invasive Cystic Hypersecretory Carcinoma of Breast: A Rare and Under Diagnosed Variant of Ductal Carcinoma
title_full Invasive Cystic Hypersecretory Carcinoma of Breast: A Rare and Under Diagnosed Variant of Ductal Carcinoma
title_fullStr Invasive Cystic Hypersecretory Carcinoma of Breast: A Rare and Under Diagnosed Variant of Ductal Carcinoma
title_full_unstemmed Invasive Cystic Hypersecretory Carcinoma of Breast: A Rare and Under Diagnosed Variant of Ductal Carcinoma
title_short Invasive Cystic Hypersecretory Carcinoma of Breast: A Rare and Under Diagnosed Variant of Ductal Carcinoma
title_sort invasive cystic hypersecretory carcinoma of breast a rare and under diagnosed variant of ductal carcinoma
topic breast carcinoma
discharge
lump
mastectomy
url https://jcdr.net/articles/PDF/10098/27937_CE_F(RK)_PF1(PrGGH)_PFA(RU_PrG).pdf
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AT pritinandamishra invasivecystichypersecretorycarcinomaofbreastarareandunderdiagnosedvariantofductalcarcinoma
AT susamapatra invasivecystichypersecretorycarcinomaofbreastarareandunderdiagnosedvariantofductalcarcinoma
AT prakashkumarsasmal invasivecystichypersecretorycarcinomaofbreastarareandunderdiagnosedvariantofductalcarcinoma