Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system
An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper body and parallel-opposed fields to the lower body, with a 12 Gy prescription dose to >90% of the body...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-10-01
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| Series: | Physics and Imaging in Radiation Oncology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405631617300210 |
| Summary: | An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper body and parallel-opposed fields to the lower body, with a 12 Gy prescription dose to >90% of the body and mean lung dose ∼8 Gy. In the end-to-end test, point dose measurements had <10% error. Compared to conventional TBI, the VMAT-based TBI technique increased the mean dose to the body by ∼1.0–1.5 Gy and decreased the mean dose to the lung by ∼1.0–1.5 Gy. Overall treatment time was ∼1.5 h, similar to conventional TBI. Keywords: Total body irradiation, Volumetric modulated arc therapy, Immobilization system |
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| ISSN: | 2405-6316 |