Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system

An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper body and parallel-opposed fields to the lower body, with a 12 Gy prescription dose to >90% of the body...

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Main Authors: Luo Ouyang, Michael Folkerts, You Zhang, Brian Hrycushko, Richard Lamphier, Pam Lee, Eric Chambers, Ezequiel Ramirez, Robert Reynolds, Yulong Yan, Steve B. Jiang, Robert Timmerman, Neil Desai, Ramzi Abdulrahman, Xuejun Gu
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Physics and Imaging in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405631617300210
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author Luo Ouyang
Michael Folkerts
You Zhang
Brian Hrycushko
Richard Lamphier
Pam Lee
Eric Chambers
Ezequiel Ramirez
Robert Reynolds
Yulong Yan
Steve B. Jiang
Robert Timmerman
Neil Desai
Ramzi Abdulrahman
Xuejun Gu
author_facet Luo Ouyang
Michael Folkerts
You Zhang
Brian Hrycushko
Richard Lamphier
Pam Lee
Eric Chambers
Ezequiel Ramirez
Robert Reynolds
Yulong Yan
Steve B. Jiang
Robert Timmerman
Neil Desai
Ramzi Abdulrahman
Xuejun Gu
author_sort Luo Ouyang
collection DOAJ
description An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper body and parallel-opposed fields to the lower body, with a 12 Gy prescription dose to >90% of the body and mean lung dose ∼8 Gy. In the end-to-end test, point dose measurements had <10% error. Compared to conventional TBI, the VMAT-based TBI technique increased the mean dose to the body by ∼1.0–1.5 Gy and decreased the mean dose to the lung by ∼1.0–1.5 Gy. Overall treatment time was ∼1.5 h, similar to conventional TBI. Keywords: Total body irradiation, Volumetric modulated arc therapy, Immobilization system
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spelling doaj.art-f2cb6b1ec0454f379defa61d210fdeb52022-12-22T00:48:40ZengElsevierPhysics and Imaging in Radiation Oncology2405-63162017-10-0142225Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization systemLuo Ouyang0Michael Folkerts1You Zhang2Brian Hrycushko3Richard Lamphier4Pam Lee5Eric Chambers6Ezequiel Ramirez7Robert Reynolds8Yulong Yan9Steve B. Jiang10Robert Timmerman11Neil Desai12Ramzi Abdulrahman13Xuejun Gu14Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Radiation Oncology, Torrance Memorial Medical Center, Torrance, CA 90505, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Radiation Oncology, Texas Tech University Health Science Center, Lubbock, TX 79415, USADepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Corresponding author.An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper body and parallel-opposed fields to the lower body, with a 12 Gy prescription dose to >90% of the body and mean lung dose ∼8 Gy. In the end-to-end test, point dose measurements had <10% error. Compared to conventional TBI, the VMAT-based TBI technique increased the mean dose to the body by ∼1.0–1.5 Gy and decreased the mean dose to the lung by ∼1.0–1.5 Gy. Overall treatment time was ∼1.5 h, similar to conventional TBI. Keywords: Total body irradiation, Volumetric modulated arc therapy, Immobilization systemhttp://www.sciencedirect.com/science/article/pii/S2405631617300210
spellingShingle Luo Ouyang
Michael Folkerts
You Zhang
Brian Hrycushko
Richard Lamphier
Pam Lee
Eric Chambers
Ezequiel Ramirez
Robert Reynolds
Yulong Yan
Steve B. Jiang
Robert Timmerman
Neil Desai
Ramzi Abdulrahman
Xuejun Gu
Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system
Physics and Imaging in Radiation Oncology
title Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system
title_full Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system
title_fullStr Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system
title_full_unstemmed Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system
title_short Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system
title_sort volumetric modulated arc therapy based total body irradiation workflow and clinical experience with an indexed rotational immobilization system
url http://www.sciencedirect.com/science/article/pii/S2405631617300210
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