Electron Transfer via Helical Oligopeptide to Laccase Including Chiral Schiff Base Copper Mediators
The oxygen reduction efficiency of a laccase-modified electrode was found to depend on the chirality of the oligopeptide linker used to bind the enzyme to the surface. At the same time, the electron transfer between the cathode electrode and the enzyme is improved by using a copper(II) complex with...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-05-01
|
| Series: | Symmetry |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-8994/12/5/808 |
| _version_ | 1797568203961925632 |
|---|---|
| author | Kumpei Kashiwagi Francesco Tassinari Tomoyuki Haraguchi Koyel Banerjee-Gosh Takashiro Akitsu Ron Naaman |
| author_facet | Kumpei Kashiwagi Francesco Tassinari Tomoyuki Haraguchi Koyel Banerjee-Gosh Takashiro Akitsu Ron Naaman |
| author_sort | Kumpei Kashiwagi |
| collection | DOAJ |
| description | The oxygen reduction efficiency of a laccase-modified electrode was found to depend on the chirality of the oligopeptide linker used to bind the enzyme to the surface. At the same time, the electron transfer between the cathode electrode and the enzyme is improved by using a copper(II) complex with amino-acid derivative Schiff base ligand with/without azobenzene moiety as a mediator. The increased electrochemical current under both O<sub>2</sub> and N<sub>2</sub> proves that both the mediators are active towards the enzyme. |
| first_indexed | 2024-03-10T19:53:07Z |
| format | Article |
| id | doaj.art-f2cf1d070f234716bbd6a146c6dc13c5 |
| institution | Directory Open Access Journal |
| issn | 2073-8994 |
| language | English |
| last_indexed | 2024-03-10T19:53:07Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Symmetry |
| spelling | doaj.art-f2cf1d070f234716bbd6a146c6dc13c52023-11-20T00:14:47ZengMDPI AGSymmetry2073-89942020-05-0112580810.3390/sym12050808Electron Transfer via Helical Oligopeptide to Laccase Including Chiral Schiff Base Copper MediatorsKumpei Kashiwagi0Francesco Tassinari1Tomoyuki Haraguchi2Koyel Banerjee-Gosh3Takashiro Akitsu4Ron Naaman5Department of Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, JapanDepartment of Chemical and Biological Physics, Weizmann Institute of Science, 234 Herzl Street, 76100 Rehovot, IsraelDepartment of Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, JapanDepartment of Chemical and Biological Physics, Weizmann Institute of Science, 234 Herzl Street, 76100 Rehovot, IsraelDepartment of Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, JapanDepartment of Chemical and Biological Physics, Weizmann Institute of Science, 234 Herzl Street, 76100 Rehovot, IsraelThe oxygen reduction efficiency of a laccase-modified electrode was found to depend on the chirality of the oligopeptide linker used to bind the enzyme to the surface. At the same time, the electron transfer between the cathode electrode and the enzyme is improved by using a copper(II) complex with amino-acid derivative Schiff base ligand with/without azobenzene moiety as a mediator. The increased electrochemical current under both O<sub>2</sub> and N<sub>2</sub> proves that both the mediators are active towards the enzyme.https://www.mdpi.com/2073-8994/12/5/808chiralityoligopeptidelaccasecopper complexelectron transfer |
| spellingShingle | Kumpei Kashiwagi Francesco Tassinari Tomoyuki Haraguchi Koyel Banerjee-Gosh Takashiro Akitsu Ron Naaman Electron Transfer via Helical Oligopeptide to Laccase Including Chiral Schiff Base Copper Mediators Symmetry chirality oligopeptide laccase copper complex electron transfer |
| title | Electron Transfer via Helical Oligopeptide to Laccase Including Chiral Schiff Base Copper Mediators |
| title_full | Electron Transfer via Helical Oligopeptide to Laccase Including Chiral Schiff Base Copper Mediators |
| title_fullStr | Electron Transfer via Helical Oligopeptide to Laccase Including Chiral Schiff Base Copper Mediators |
| title_full_unstemmed | Electron Transfer via Helical Oligopeptide to Laccase Including Chiral Schiff Base Copper Mediators |
| title_short | Electron Transfer via Helical Oligopeptide to Laccase Including Chiral Schiff Base Copper Mediators |
| title_sort | electron transfer via helical oligopeptide to laccase including chiral schiff base copper mediators |
| topic | chirality oligopeptide laccase copper complex electron transfer |
| url | https://www.mdpi.com/2073-8994/12/5/808 |
| work_keys_str_mv | AT kumpeikashiwagi electrontransferviahelicaloligopeptidetolaccaseincludingchiralschiffbasecoppermediators AT francescotassinari electrontransferviahelicaloligopeptidetolaccaseincludingchiralschiffbasecoppermediators AT tomoyukiharaguchi electrontransferviahelicaloligopeptidetolaccaseincludingchiralschiffbasecoppermediators AT koyelbanerjeegosh electrontransferviahelicaloligopeptidetolaccaseincludingchiralschiffbasecoppermediators AT takashiroakitsu electrontransferviahelicaloligopeptidetolaccaseincludingchiralschiffbasecoppermediators AT ronnaaman electrontransferviahelicaloligopeptidetolaccaseincludingchiralschiffbasecoppermediators |