A study on childhood microbial keratitis in South India
Purpose: The aim of this study was to determine the predisposing risk factors, clinical characteristics, microbiological profile, and visual and functional treatment outcome of microbial keratitis including viral keratitis in children. Methods: A prospective study was carried out in a tertiary care...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=3;spage=841;epage=846;aulast=Chandratreya |
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| author | Madhura P Chandratreya Deepthi Mudduluru Anitha Venugopal Anitt K Varghese Aditya S Ghorpade |
| author_facet | Madhura P Chandratreya Deepthi Mudduluru Anitha Venugopal Anitt K Varghese Aditya S Ghorpade |
| author_sort | Madhura P Chandratreya |
| collection | DOAJ |
| description | Purpose: The aim of this study was to determine the predisposing risk factors, clinical characteristics, microbiological profile, and visual and functional treatment outcome of microbial keratitis including viral keratitis in children. Methods: A prospective study was carried out in a tertiary care institute over a period of 18 months on 73 pediatric patients. Data collected was analyzed for demographics of the patient population, causative organisms, and management outcome in terms of visual and functional outcome. Results: Patients in the age group from 1 month to 16 years were included, with a mean age of 10.81 years. Trauma was the commonest risk factor (40.9%), with unidentified foreign body fall being the most common (32.3%). No predisposing factors were identified in 50% of cases. Also, 36.8% of eyes were culture positive, with bacterial isolates in 17.9% and fungus in 82.1%. Moreover, 7.1% eyes were culture positive for Streptococcus pneumoniae and Pseudomonas aeruginosa each. Fusarium species (67.8%) was the commonest fungal pathogen, followed by Aspergillus species (10.7%). Also, 11.8% were clinically diagnosed as viral keratitis. No growth was found in 63.2% of patients. Treatment with broad-spectrum antibiotics/antifungals was administered in all cases. At the final follow-up, 87.8% achieved a best corrected visual acuity (BCVA) of 6/12 or better. Therapeutic penetrating keratoplasty (TPK) was required by 2.6% of eyes. Conclusion: Trauma was the major cause for pediatric keratitis. Majority of the eyes responded well to medical treatment, with only two eyes needing TPK. Early diagnosis and prompt management helped majority of the eyes to achieve a good visual acuity after the resolution of keratitis. |
| first_indexed | 2024-03-13T10:36:35Z |
| format | Article |
| id | doaj.art-f2cfbf2d57d64c4db20fd233858e3711 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-03-13T10:36:35Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-f2cfbf2d57d64c4db20fd233858e37112023-05-18T06:11:44ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892023-01-0171384184610.4103/ijo.IJO_1314_22A study on childhood microbial keratitis in South IndiaMadhura P ChandratreyaDeepthi MudduluruAnitha VenugopalAnitt K VargheseAditya S GhorpadePurpose: The aim of this study was to determine the predisposing risk factors, clinical characteristics, microbiological profile, and visual and functional treatment outcome of microbial keratitis including viral keratitis in children. Methods: A prospective study was carried out in a tertiary care institute over a period of 18 months on 73 pediatric patients. Data collected was analyzed for demographics of the patient population, causative organisms, and management outcome in terms of visual and functional outcome. Results: Patients in the age group from 1 month to 16 years were included, with a mean age of 10.81 years. Trauma was the commonest risk factor (40.9%), with unidentified foreign body fall being the most common (32.3%). No predisposing factors were identified in 50% of cases. Also, 36.8% of eyes were culture positive, with bacterial isolates in 17.9% and fungus in 82.1%. Moreover, 7.1% eyes were culture positive for Streptococcus pneumoniae and Pseudomonas aeruginosa each. Fusarium species (67.8%) was the commonest fungal pathogen, followed by Aspergillus species (10.7%). Also, 11.8% were clinically diagnosed as viral keratitis. No growth was found in 63.2% of patients. Treatment with broad-spectrum antibiotics/antifungals was administered in all cases. At the final follow-up, 87.8% achieved a best corrected visual acuity (BCVA) of 6/12 or better. Therapeutic penetrating keratoplasty (TPK) was required by 2.6% of eyes. Conclusion: Trauma was the major cause for pediatric keratitis. Majority of the eyes responded well to medical treatment, with only two eyes needing TPK. Early diagnosis and prompt management helped majority of the eyes to achieve a good visual acuity after the resolution of keratitis.http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=3;spage=841;epage=846;aulast=Chandratreyamicrobial keratitispediatricviral keratitisvisual outcome |
| spellingShingle | Madhura P Chandratreya Deepthi Mudduluru Anitha Venugopal Anitt K Varghese Aditya S Ghorpade A study on childhood microbial keratitis in South India Indian Journal of Ophthalmology microbial keratitis pediatric viral keratitis visual outcome |
| title | A study on childhood microbial keratitis in South India |
| title_full | A study on childhood microbial keratitis in South India |
| title_fullStr | A study on childhood microbial keratitis in South India |
| title_full_unstemmed | A study on childhood microbial keratitis in South India |
| title_short | A study on childhood microbial keratitis in South India |
| title_sort | study on childhood microbial keratitis in south india |
| topic | microbial keratitis pediatric viral keratitis visual outcome |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=3;spage=841;epage=846;aulast=Chandratreya |
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