Development of an Optimized Process for Functional Recombinant SARS-CoV-2 Spike S1 Receptor-Binding Domain Protein Produced in the Baculovirus Expression Vector System

Development of an Optimized Process for Functional Recombinant SARS-CoV-2 Spike S1 Receptor-Binding Domain Protein Produced in the Baculovirus Expression Vector System

To map the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and evaluate immune response variations against this virus, it is essential to set up efficient serological tests locally. The SARS-CoV-2 immunogenic proteins were very expensive and not affordable for lower- middle-in...

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Bibliographic Details
Main Authors: Mohamed Boumaiza, Ameni Chaabene, Ines Akrouti, Meriem Ben Zakour, Hana Askri, Said Salhi, Wafa Ben Hamouda, Soumaya Marzouki, Chaouki Benabdessalem, Melika Ben Ahmed, Khaled Trabelsi, Samia Rourou
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Tropical Medicine and Infectious Disease
Subjects:
multiplicity of infection
cell density at infection
SARS-CoV-2
spike S1 glycoprotein
receptor-binding domain
Sf9 cells
Online Access:https://www.mdpi.com/2414-6366/8/11/501

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