Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not
Cardiac amyloidosis (CA), caused by the deposition of insoluble amyloid fibrils, impairs different cardiac structures, altering not only left ventricle (LV) systo-diastolic function but also atrial function and the conduction system. The consequences of the involvement of the cardiac electrical syst...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/11/2888 |
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| author | Alessia Argirò Annamaria Del Franco Carlotta Mazzoni Marco Allinovi Alessia Tomberli Roberto Tarquini Carlo Di Mario Federico Perfetto Francesco Cappelli Mattia Zampieri |
| author_facet | Alessia Argirò Annamaria Del Franco Carlotta Mazzoni Marco Allinovi Alessia Tomberli Roberto Tarquini Carlo Di Mario Federico Perfetto Francesco Cappelli Mattia Zampieri |
| author_sort | Alessia Argirò |
| collection | DOAJ |
| description | Cardiac amyloidosis (CA), caused by the deposition of insoluble amyloid fibrils, impairs different cardiac structures, altering not only left ventricle (LV) systo-diastolic function but also atrial function and the conduction system. The consequences of the involvement of the cardiac electrical system deserve more attention, as well as the study of the underlying molecular mechanisms. This is an issue of considerable interest, given the conflicting data on the effectiveness of conventional antiarrhythmic strategies. Therefore, this review aims at summarizing the arrhythmic burden related to CA and the available evidence on antiarrhythmic treatment in this population. |
| first_indexed | 2024-03-09T19:15:42Z |
| format | Article |
| id | doaj.art-f2d8bcea9d6e4cf592f6dfb16c0f0cf8 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T19:15:42Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-f2d8bcea9d6e4cf592f6dfb16c0f0cf82023-11-24T03:52:19ZengMDPI AGBiomedicines2227-90592022-11-011011288810.3390/biomedicines10112888Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do NotAlessia Argirò0Annamaria Del Franco1Carlotta Mazzoni2Marco Allinovi3Alessia Tomberli4Roberto Tarquini5Carlo Di Mario6Federico Perfetto7Francesco Cappelli8Mattia Zampieri9Tuscan Regional Amyloidosis Centre, Careggi University Hospital, 50134 Florence, ItalyTuscan Regional Amyloidosis Centre, Careggi University Hospital, 50134 Florence, ItalyTuscan Regional Amyloidosis Centre, Careggi University Hospital, 50134 Florence, ItalyTuscan Regional Amyloidosis Centre, Careggi University Hospital, 50134 Florence, ItalyTuscan Regional Amyloidosis Centre, Careggi University Hospital, 50134 Florence, ItalyDepartment of Internal Medicine I, San Giuseppe Hospital, 50053 Empoli, ItalyStructural Interventional Cardiology Department, Careggi University Hospital, 50134 Florence, ItalyTuscan Regional Amyloidosis Centre, Careggi University Hospital, 50134 Florence, ItalyTuscan Regional Amyloidosis Centre, Careggi University Hospital, 50134 Florence, ItalyTuscan Regional Amyloidosis Centre, Careggi University Hospital, 50134 Florence, ItalyCardiac amyloidosis (CA), caused by the deposition of insoluble amyloid fibrils, impairs different cardiac structures, altering not only left ventricle (LV) systo-diastolic function but also atrial function and the conduction system. The consequences of the involvement of the cardiac electrical system deserve more attention, as well as the study of the underlying molecular mechanisms. This is an issue of considerable interest, given the conflicting data on the effectiveness of conventional antiarrhythmic strategies. Therefore, this review aims at summarizing the arrhythmic burden related to CA and the available evidence on antiarrhythmic treatment in this population.https://www.mdpi.com/2227-9059/10/11/2888arrhythmiasatrial fibrillationpacemaker implantationcardiac amyloidosis |
| spellingShingle | Alessia Argirò Annamaria Del Franco Carlotta Mazzoni Marco Allinovi Alessia Tomberli Roberto Tarquini Carlo Di Mario Federico Perfetto Francesco Cappelli Mattia Zampieri Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not Biomedicines arrhythmias atrial fibrillation pacemaker implantation cardiac amyloidosis |
| title | Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not |
| title_full | Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not |
| title_fullStr | Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not |
| title_full_unstemmed | Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not |
| title_short | Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not |
| title_sort | arrhythmic burden in cardiac amyloidosis what we know and what we do not |
| topic | arrhythmias atrial fibrillation pacemaker implantation cardiac amyloidosis |
| url | https://www.mdpi.com/2227-9059/10/11/2888 |
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