Clinical image: rare localization of a giant recurrent malignant meningioma

Meningiomas are the most common benign brain tumors. Malignant meningioma is a rare subtype with a high recurrence rate and poor prognosis. Most meningiomas grow intracranially, whereas extracranial growth of meningiomas has been rarely reported. We herein report a rare case of a giant malignant men...

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Main Authors: Ibrahim Halil Türkbeyler, Mehmet Akif Sarıca, Taner Babacan, İsmail Dilli
Format: Article
Language:English
Published: PAGEPress Publications 2014-05-01
Series:Italian Journal of Medicine
Subjects:
Online Access:http://www.italjmed.org/index.php/ijm/article/view/438
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author Ibrahim Halil Türkbeyler
Mehmet Akif Sarıca
Taner Babacan
İsmail Dilli
author_facet Ibrahim Halil Türkbeyler
Mehmet Akif Sarıca
Taner Babacan
İsmail Dilli
author_sort Ibrahim Halil Türkbeyler
collection DOAJ
description Meningiomas are the most common benign brain tumors. Malignant meningioma is a rare subtype with a high recurrence rate and poor prognosis. Most meningiomas grow intracranially, whereas extracranial growth of meningiomas has been rarely reported. We herein report a rare case of a giant malignant meningioma with multiple recurrences. A 56-year old man presented with a forehead swelling. He had a history of repeated craniotomy for a frontal sinus invasion. The tumor recurred one year after the last surgery on the forehead and was classified as a giant meningioma at admission to our hospital. Neurosurgeons performed total resection of the giant meningioma and reconstructed the defect. However, six months after the surgery, the tumor recurred at the same site. The patient refused surgery and underwent cyber-knife treatment. An hydroxyurea treatment was initiated after radiotherapy, but the tumor progressed. Temozolomide and cisplatin treatment was started. A valuable clinical improvement was observed after the initiation of the first cycle. After completion of two cycles of systemic chemotherapy, the patient will be assessed clinically and radiologically.
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spelling doaj.art-f2d9d1f800cc44188c36050c3e8f69132023-12-02T00:49:01ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522014-05-018213213410.4081/itjm.2014.438422Clinical image: rare localization of a giant recurrent malignant meningiomaIbrahim Halil Türkbeyler0Mehmet Akif Sarıca1Taner Babacan2İsmail Dilli3Department of Internal Medicine, Adiyaman University School of MedicineDepartment of Internal Medicine, Adiyaman University School of MedicineDepartment of Internal Medicine, Adiyaman University School of MedicineDepartment of Internal Medicine, Adiyaman University School of MedicineMeningiomas are the most common benign brain tumors. Malignant meningioma is a rare subtype with a high recurrence rate and poor prognosis. Most meningiomas grow intracranially, whereas extracranial growth of meningiomas has been rarely reported. We herein report a rare case of a giant malignant meningioma with multiple recurrences. A 56-year old man presented with a forehead swelling. He had a history of repeated craniotomy for a frontal sinus invasion. The tumor recurred one year after the last surgery on the forehead and was classified as a giant meningioma at admission to our hospital. Neurosurgeons performed total resection of the giant meningioma and reconstructed the defect. However, six months after the surgery, the tumor recurred at the same site. The patient refused surgery and underwent cyber-knife treatment. An hydroxyurea treatment was initiated after radiotherapy, but the tumor progressed. Temozolomide and cisplatin treatment was started. A valuable clinical improvement was observed after the initiation of the first cycle. After completion of two cycles of systemic chemotherapy, the patient will be assessed clinically and radiologically.http://www.italjmed.org/index.php/ijm/article/view/438localization, malignant meningioma.
spellingShingle Ibrahim Halil Türkbeyler
Mehmet Akif Sarıca
Taner Babacan
İsmail Dilli
Clinical image: rare localization of a giant recurrent malignant meningioma
Italian Journal of Medicine
localization, malignant meningioma.
title Clinical image: rare localization of a giant recurrent malignant meningioma
title_full Clinical image: rare localization of a giant recurrent malignant meningioma
title_fullStr Clinical image: rare localization of a giant recurrent malignant meningioma
title_full_unstemmed Clinical image: rare localization of a giant recurrent malignant meningioma
title_short Clinical image: rare localization of a giant recurrent malignant meningioma
title_sort clinical image rare localization of a giant recurrent malignant meningioma
topic localization, malignant meningioma.
url http://www.italjmed.org/index.php/ijm/article/view/438
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AT mehmetakifsarıca clinicalimagerarelocalizationofagiantrecurrentmalignantmeningioma
AT tanerbabacan clinicalimagerarelocalizationofagiantrecurrentmalignantmeningioma
AT ismaildilli clinicalimagerarelocalizationofagiantrecurrentmalignantmeningioma