Pure Embryonal Cell Carcinoma: A Rare Entity
Malignancy of the testes constitutes only one percent of all male cancers. Most testicular malignancies are Germ Cell Tumours (GCTs), which are broadly categorised into seminomatous and non-seminomatous types. Non seminomatous GCTs are further classified into several subtypes based on their histopat...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2023-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/18695/65227_CE[Ra1]_F(IS)_PF1(AP_IS)_QC(AN_RDW_IS)_PFA(KM)_PB(AP_OM)_PN(KM).pdf |
| _version_ | 1797555361918484480 |
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| author | Neha Jaiswal Anita Sajjanar Vaishnavi Mishra |
| author_facet | Neha Jaiswal Anita Sajjanar Vaishnavi Mishra |
| author_sort | Neha Jaiswal |
| collection | DOAJ |
| description | Malignancy of the testes constitutes only one percent of all male cancers. Most testicular malignancies are Germ Cell Tumours (GCTs), which are broadly categorised into seminomatous and non-seminomatous types. Non seminomatous GCTs are further classified into several subtypes based on their histopathological features. This case report presents a case of Pure Embryonal
Cell Carcinoma (PECC) of the testes in a 32-year-old male. The diagnostic work-up involved a detailed medical history, physical examination, and imaging tests, including a scrotal ultrasound and Positron Emission Tomography-Computed Tomography (PET/CT) scan. These tests helped identify a testicular mass without metastasis. Additionally, serum tumour markers such as Alpha Fetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase were elevated, further confirming the presence of testicular malignancy. The management of the patient included surgery and chemotherapy. Histopathology and
immunohistochemistry were performed, resulting in a diagnosis of pure embryonal carcinoma. This case highlights the significance of timely diagnosis and prompt management in improving the prognosis of patients with PECC. |
| first_indexed | 2024-03-10T16:46:21Z |
| format | Article |
| id | doaj.art-f2da381451374ea186d67d837eaf7469 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-10T16:46:21Z |
| publishDate | 2023-11-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-f2da381451374ea186d67d837eaf74692023-11-20T11:37:25ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-11-011711040610.7860/JCDR/2023/65227.18695Pure Embryonal Cell Carcinoma: A Rare EntityNeha Jaiswal0Anita Sajjanar1Vaishnavi Mishra2Senior Resident, Department of Pathology, Datta Meghe Institute of Higher Education and Research, Nagpur, Maharashtra, India.Professor, Department of Pathology, Datta Meghe Institute of Higher Education and Research, Nagpur, Maharashtra, India.Junior Research Fellow, Department of Microbiology, Jawaharlal Nehru Medical College, Nagpur, Maharashtra, India.Malignancy of the testes constitutes only one percent of all male cancers. Most testicular malignancies are Germ Cell Tumours (GCTs), which are broadly categorised into seminomatous and non-seminomatous types. Non seminomatous GCTs are further classified into several subtypes based on their histopathological features. This case report presents a case of Pure Embryonal Cell Carcinoma (PECC) of the testes in a 32-year-old male. The diagnostic work-up involved a detailed medical history, physical examination, and imaging tests, including a scrotal ultrasound and Positron Emission Tomography-Computed Tomography (PET/CT) scan. These tests helped identify a testicular mass without metastasis. Additionally, serum tumour markers such as Alpha Fetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase were elevated, further confirming the presence of testicular malignancy. The management of the patient included surgery and chemotherapy. Histopathology and immunohistochemistry were performed, resulting in a diagnosis of pure embryonal carcinoma. This case highlights the significance of timely diagnosis and prompt management in improving the prognosis of patients with PECC.https://www.jcdr.net/articles/PDF/18695/65227_CE[Ra1]_F(IS)_PF1(AP_IS)_QC(AN_RDW_IS)_PFA(KM)_PB(AP_OM)_PN(KM).pdfgerm cell tumourmetastasistesticular tumour |
| spellingShingle | Neha Jaiswal Anita Sajjanar Vaishnavi Mishra Pure Embryonal Cell Carcinoma: A Rare Entity Journal of Clinical and Diagnostic Research germ cell tumour metastasis testicular tumour |
| title | Pure Embryonal Cell Carcinoma: A Rare Entity |
| title_full | Pure Embryonal Cell Carcinoma: A Rare Entity |
| title_fullStr | Pure Embryonal Cell Carcinoma: A Rare Entity |
| title_full_unstemmed | Pure Embryonal Cell Carcinoma: A Rare Entity |
| title_short | Pure Embryonal Cell Carcinoma: A Rare Entity |
| title_sort | pure embryonal cell carcinoma a rare entity |
| topic | germ cell tumour metastasis testicular tumour |
| url | https://www.jcdr.net/articles/PDF/18695/65227_CE[Ra1]_F(IS)_PF1(AP_IS)_QC(AN_RDW_IS)_PFA(KM)_PB(AP_OM)_PN(KM).pdf |
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