Asymptomatic bacteriuria in recurrent UTI – to treat or not to treat

Asymptomatic bacteriuria (ABU) is a common clinical condition that often leads to unnecessary antimicrobial use. The reduction of antibiotic overuse for ABU is consequently an important issue for antimicrobial stewardship to reduce the emergence of multidrug resistant strains. In the clinical settin...

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Main Authors: Cai, Tommaso, Bartoletti, Riccardo
Format: Article
Language:English
Published: German Medical Science GMS Publishing House 2017-12-01
Series:GMS Infectious Diseases
Online Access:http://www.egms.de/static/en/journals/id/2017-5/id000035.shtml
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author Cai, Tommaso
Bartoletti, Riccardo
author_facet Cai, Tommaso
Bartoletti, Riccardo
author_sort Cai, Tommaso
collection DOAJ
description Asymptomatic bacteriuria (ABU) is a common clinical condition that often leads to unnecessary antimicrobial use. The reduction of antibiotic overuse for ABU is consequently an important issue for antimicrobial stewardship to reduce the emergence of multidrug resistant strains. In the clinical setting we have an important issue that requires special attention: the role of ABU in women affected by recurrent urinary tract infections (rUTIs). In everyday clinical practice, young women affected by rUTI show after antibiotic treatment asymptomatic periods associated sometimes with or without bacteriuria. Although it is not recommended, the majority of women with ABU is treated with poor results and occasionally a selection of multidrug-resistant bacteria can be observed. Recent studies demonstrated that ABU should not be treated in young women affected by rUTI, because it may play even a protective role in preventing symptomatic episodes, particularly when Enterococcus faecalis has been isolated. Moreover, ABU treatment is associated with a higher occurrence of antibiotic-resistant bacteria, indicating that ABU treatment in women with rUTIs is even potentially dangerous.
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spelling doaj.art-f2dae58e8e47455bbaba65a86b972d152022-12-22T00:38:34ZengGerman Medical Science GMS Publishing HouseGMS Infectious Diseases2195-88312017-12-015Doc0910.3205/id000035Asymptomatic bacteriuria in recurrent UTI – to treat or not to treatCai, Tommaso0Bartoletti, Riccardo1Department of Urology, Santa Chiara Regional Hospital, Trento, ItalyDepartment of Translational Research and New Technologies, University of Pisa, ItalyAsymptomatic bacteriuria (ABU) is a common clinical condition that often leads to unnecessary antimicrobial use. The reduction of antibiotic overuse for ABU is consequently an important issue for antimicrobial stewardship to reduce the emergence of multidrug resistant strains. In the clinical setting we have an important issue that requires special attention: the role of ABU in women affected by recurrent urinary tract infections (rUTIs). In everyday clinical practice, young women affected by rUTI show after antibiotic treatment asymptomatic periods associated sometimes with or without bacteriuria. Although it is not recommended, the majority of women with ABU is treated with poor results and occasionally a selection of multidrug-resistant bacteria can be observed. Recent studies demonstrated that ABU should not be treated in young women affected by rUTI, because it may play even a protective role in preventing symptomatic episodes, particularly when Enterococcus faecalis has been isolated. Moreover, ABU treatment is associated with a higher occurrence of antibiotic-resistant bacteria, indicating that ABU treatment in women with rUTIs is even potentially dangerous.http://www.egms.de/static/en/journals/id/2017-5/id000035.shtml
spellingShingle Cai, Tommaso
Bartoletti, Riccardo
Asymptomatic bacteriuria in recurrent UTI – to treat or not to treat
GMS Infectious Diseases
title Asymptomatic bacteriuria in recurrent UTI – to treat or not to treat
title_full Asymptomatic bacteriuria in recurrent UTI – to treat or not to treat
title_fullStr Asymptomatic bacteriuria in recurrent UTI – to treat or not to treat
title_full_unstemmed Asymptomatic bacteriuria in recurrent UTI – to treat or not to treat
title_short Asymptomatic bacteriuria in recurrent UTI – to treat or not to treat
title_sort asymptomatic bacteriuria in recurrent uti to treat or not to treat
url http://www.egms.de/static/en/journals/id/2017-5/id000035.shtml
work_keys_str_mv AT caitommaso asymptomaticbacteriuriainrecurrentutitotreatornottotreat
AT bartolettiriccardo asymptomaticbacteriuriainrecurrentutitotreatornottotreat